Hwang, Hau-Hsuan - Professor
Hwang, Hau-Hsuan Professor 繁體中文 English
Full-time teacher
Physiology
04-22840416#412、413

Study of mechanisms of plant endophytic bacteria in promoting plant growth, Study of molecular mechanisms of Agrobacterium pathogenesis, Establishment of Agrobacterium-mediated plant transformation systems

Education

Graduate from Major in Degree Period
Purdue University Department of Biological Sciences Ph.D. 1998/08-2004/05
National Taiwan University Department of Botany B.S. 1993/09-1997/06

Experience / Honor

Experience

Organization Department Title Period
National Chung Hsing University Department of Life Sciences Professor 2021/02-
National Chung Hsing University Department of Life Sciences Associate Professor 2014/02-2021/02
National Chung Hsing University Department of Life Sciences Assistant Professor 2006/08 -2014/01
Academia Sinica Institute of Plant and Microbial Biology Postdoc 2004/07 - 2006/07
Purdue University Department of Biological Sciences Postdoc 2004/05 - 2004/06
National Taiwan University Department of Botany Research Assistant 1997/07-1998/07

Honor

Year

Title

2022. 08

Excellent Service Award of National Chung Hsing University

2020. 08

Distinguished Associate Professor Award of National Chung Hsing University

2019.08

Future tech Breakthrough Award of Ministry of Science and Technology, Taiwan

2018. 03

Innovation Teaching Award of National Chung Hsing University

2017. 08

Outstanding Young Scientist Award of National Chung Hsing University

2014. 08

Excellent Service Award of National Chung Hsing University

2012. 11

Distinguished Teaching Award I of National Chung Hsing University

Research

Our researches are mainly on studies of plant-microbe interactions, including (1) Study of mechanisms of plant endophytic bacteria in promoting plant growth, (2) Study of molecular mechanisms of Agrobacterium pathogenesis.

(1) Study of mechanisms of plant endophytic bacteria in promoting plant growth

Global warming and climate change have contributed to the rise of weather extremes. Severe drought and soil salinization increase because of rising temperatures. Economically important crop production and plant growth and development are hindered when facing various abiotic stresses. Plant endophytic bacteria live inside host plants without causing visible harm and can be isolated from surface-sterilized plant tissues. Using plant endophytic bacteria to stimulate plant growth and increase environmental stress tolerance has become an alternative approach. By isolation and functional characterization of these beneficial plant endophytic bacteria, we will be able to understand interactions between the plant endophytic bacteria and host plants, broaden the application aspects of plant endophytes, and finally increase abilities of economic important crops to withstand global climate change.  

 

(2) Study of molecular mechanisms of Agrobacterium pathogenesis.

The Agrobacterium tumefaciens has a unique ability to the transfer a specific DNA fragment (the T-DNA), processed from a bacterial tumor-inducing (Ti) plasmid, into plant cells and express the foreign genes in infected plant cells. The Agrobacterium-mediated transformation has become the most commonly used method for generating transgenic plants and genetic modified crops. By functional characterization of plant and bacteria genes involved in Agrobacterium virulence, we will be able to understand molecular mechanism of Agrobacterium infection process, improve Agrobacterium-mediated plant transformation efficiencies, and expand its application in the agricultural biotechnology industry.

Journal Article

作者
出版年
著作篇名
期刊名稱
卷號
頁數
資料庫
IF值
排名百分比
Hung, SHW; Huang, TC; Lai, YC; Wu, IC; Liu, CH; Huarng, YF; Hwang, HH; Chiang, EPI; Kuo, CH; and Huang, CC
 2023
 Endophytic biostimulants for smart agriculture: Burkholderia seminalis 869T2 benefits heading leafy vegetables in-field management in Taiwan.
  AGRONOMY
 13
 967
 SCI
 
 
Hwang, HH; Chien, PR; Huang, FC; Yeh, PH; Hung, SHW; Deng, WL; Huang, CC
   2022
  A plant endophytic bacterium Priestia megaterium strain BP-R2 isolated from the halophyte Bolboschoenus planiculmis enhances plant growth under salt and drought stresses.
  MICROORGANISMS
 10
 2047
 SCI
 
 
Chen,PM;Tsai,CH;Huang,CC;Hwang,HH;Li,JR;Liu,CC;Ko,HA;Chiang,EPI
  2022
  Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
 23
 481
 SCI
 
 
Huang,FC;Chi,SF;Chien,PR;Liu,YT;Chang,HN;Lin,CS;Hwang,HH
  2021
  Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process
  PLANT AND CELL PHYSIOLOGY
 62
 1572-1588
 SCI
 
 
Hwang,HH;Chien,PR;Huang,FC;Hung,SH;Kuo,CH;Deng,WL;Chiang,EPI;Huang,CC
  2021
  A Plant Endophytic Bacterium, Burkholderia seminalis Strain 869T2, Promotes Plant Growth in Arabidopsis, Pak Choi, Chinese Amaranth, Lettuces, and Other Vegetables
  MICROORGANISMS
 9
 1703
 SCI
 
 
Huang,FC;Hwang,HH
  2020
  Arabidopsis RETICULON-LIKE4 (RTNLB4) Protein Participates in Agrobacterium Infection and VirB2 Peptide-Induced Plant Defense Response
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
 21
 1722
 SCI
 
 
Hwang,HH;Wang,CH;Chen,HH;Ho,JF;Chi,SF;Huang,FC;Yen,HE
  2019
  Effective Agrobacterium-mediated transformation protocols for callus and roots of halophyte ice plant (Mesembryanthemum crystallinum)
  BOTANICAL STUDIES
 60
  1
 SCI
 
 
Hwang,HH;Wang,CH;Huang,HW;Chiang,CP;Chi,SF;Huang,FC;Yen,HCE
  2019
  Functional analysis of McSnRK1 (SNF1-related protein kinase 1) in regulating Na/K homeostasis in transgenic cultured cells and roots of halophyte Mesembryanthemum crystallinum
  PLANT CELL REPORTS
 38
 915-926
 SCI
 
 
Huang,FC;Fu,BJ;Liu,YT;Chang,YR;Chi,SF;Chien,PR;Huang,SC;Hwang,HH
  2018
  Arabidopsis RETICULON-LIKE3 (RTNLB3) and RTNLB8 Participate in Agrobacterium-Mediated Plant Transformation
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
 19
 638
 SCI
 
 
Haryono,M;Tsai,YM;Lin,CT;Huang,FC;Ye,YC;Deng,WL;Hwang,HH;Kuo,CH
  2018
  Presence of an Agrobacterium-Type Tumor-Inducing Plasmid in Neorhizobium sp. NCHU2750 and the Link to Phytopathogenicity
  GENOME BIOLOGY AND EVOLUTION
 10
 3188-3195
 SCI
 
 
Wang,PJ;Yang,WK;Lin,CH;Hwang,HH;Lee,TH
  2017
  FXYD8, a Novel Regulator of Renal Na+/K+-ATPase in the Euryhaline Teleost, Tetraodon nigroviridis
  FRONTIERS IN PHYSIOLOGY
 8
 576
 SCI
 
 
Sun,LP;Xu,X;Hwang,HH;Wang,X;Su,KY;Chen,YLS
  2016
  Dichloromethane extracts of propolis protect cell from oxygen-glucose deprivation-induced oxidative stress via reducing apoptosis
  FOOD & NUTRITION RESEARCH
 60
 30081
 SCI
 
 
Hwang,HH;Liu,YT;Huang,SC;Tung,CY;Huang,FC;Tsai,YL;Cheng,TF;Lai,EM
  2015
  Overexpression of the HspL Promotes Agrobacterium tumefaciens Virulence in Arabidopsis Under Heat Shock Conditions
  PHYTOPATHOLOGY
 105
 160-168
 SCI
 
 
Hwang,HH;Galvin,SB;Lai,EM
  2015
  Editorial: "Agrobacterium biology and its application to transgenic plant production"
  FRONTIERS IN PLANT SCIENCE
 6
 265
 SCI
 
 
Hwang,HH;Yang,FJ;Cheng,TF;Chen,YC;Lee,YL;Tsai,YL;Lai,EM
  2013
  The Tzs Protein and Exogenous Cytokinin Affect Virulence Gene Expression and Bacterial Growth of Agrobacterium tumefaciens
  PHYTOPATHOLOGY
 103
 888-899
 SCI
 
 
Hwang,HH;Wu,ET;Liu,SY;Chang,SC;Tzeng,KC;Kado,CI
  2013
  Characterization and host range of five tumorigenic Agrobacterium tumefaciens strains and possible application in plant transient transformation assays
  PLANT PATHOLOGY
 62
 1384-1397
 SCI
 
 
Hwang,HH;Wang,MH;Lee,YL;Tsai,YL;Li,YH;Yang,FJ;Liao,YC;Lin,SK;Lai,EM
  2010
  Agrobacterium-produced and exogenous cytokinin-modulated Agrobacterium-mediated plant transformation
  MOLECULAR PLANT PATHOLOGY
 11
 677-690
 SCI
 
 
Wang,PJ;Lin,CH;Hwang,HH;Lee,TH
  2008
  Branchial FXYD protein expression in response to salinity change and its interaction with Na+/K+-ATPase of the euryhaline teleost Tetraodon nigroviridis
  JOURNAL OF EXPERIMENTAL BIOLOGY
 211
 3750-3758
 SCI
 
 
Hwang, HH; Mysore, K; Gelvin, SB
  2006
  Transgenic Arabidopsis plants expressing Agrobacterium tumefaciens VirD2 protein are less susceptible to Agrobacterium transformation.
  MOLECULAR PLANT PATHOLOGY
 7
 473-484
 SCI
 
 
Lai, EM; Shih, HW; Wen, SR; Cheng, MW; Hwang, HH; Chiu, SH
  2006
   A proteomic approach to identify phenolics-induced proteins in Agrobacterium tumefaciens.
  PROTEOMICS
 6
 4130-4136
 SCI
 
 
Hwang, HH; Gelvin, SB
  2004
  Plant proteins that interact with VirB2, the Agrobacterium pilin protein, mediate plant transformation.
  PLANT CELL
 16
 3148-3167
 SCI
 
 
Zhu, Y; Nam, J; Humara, JM; Mysore, KS; Lee, LY; Cao H; Valentine, L; Li, J; Kaiser, AD; Kopecky, AL; Hwang, HH; Bhattacharjee, S; Rao, PK; Tzfira, T; Rajagopal, J; Yi, H; Veena, Yadav, BS; Crane, YM; Lin, K; Larcher, Y; Gelvin, MJ; Knue, M; Ramos, C; Zhao, X; Davis, SJ; Kim, SI; Ranjith-Kumar, CT; Choi, YJ; Hallan, VK; Chattopadhyay, S; Sui, X; Ziemienowicz, A; Matthysse, AG; Citovsky, V; Hohn, B; Gelvin, SB
  2003
  Identification of Arabidopsis rat mutants.
  PLANT PHYSIOLOGY
 132
 494-505
 SCI
 
 
Hwang, H.H.
  2020
  Role of Arabidopsis RETICULON-LIKE4 (RTNLB4) in Agrobacterium infection and plant defense response
  Encyclopedia
 764
 
 
 
 
Huang, F.C., and Hwang, H.H.
  2018
  The arms race between Agrobacterium and host plants. 農桿菌新知與宿主植物的免疫攻防戰.
  Journal of Plant Medicine植物醫學
 60
 2
 
 
 
Huang, F.C., and Hwang, H.H.
  2017
  植物與病原菌的部落衝突.
  Science Development (科學發展)
 539
 44-49
 
 
 
Hwang, H.H.,* Yang, F.-J., Cheng, T.-F., and Tung, C.Y.
  2016
  細胞分裂素 ─植物的抗老化因子.
  Science Development (科學發展)
 523
 36-41
 
 
 
Hwang, H.H.
  2012
  農桿菌—自然界的基因改造者
  Science Development (科學發展)
 478
 54-59
 
 
 

Monograph

作者
出版年
專書名稱
出版地點
出版機構
 
Hwang, H.-H.,* Yu, M., and Lai, E.M.*
  2017
  The Arabidopsis Book, Agrobacterium-mediated plant transformation: biology and applications.
  美國
  ASPB
 
Hwang, H.-H., Liu, S.-Y., and Ho, C.-W.
  2019
  生命科學實驗手冊(動物暨分子生物學篇)Handbook of Life Science Experiments.
  台灣
  中興大學
 
Hwang, H.-H., Liu, S.-Y.
  2017
  生命科學實驗手冊(植物篇)Handbook of Life Science Experiments.
  台灣
  中興大學
 
Hwang, H.-H., Lai, E.M., and Gelvin, S.B.
  2015
  Agrobacterium biology and its application to transgenic plant production.
  瑞士
  Frontiers Media SA,
 
Hwang, H.-H.
  2004
  Identification of plant proteins that interact with the Agrobacterium pilin protein, VirB2.
  美國
  美國普渡大學
 

Patent

作者
發證年度
專利發明名稱
獲准國別
專利證號
Hwang, H.-H., Huang, F.-C., and Chien, P.-R.
  2021
  VirB2 peptide for increasing plant immunity and method thereof for enhancing plant capacity against pathogen infections
  Taiwan patent
  I736885
Hwang, H.-H., Wang, C.-H., and Yen, H.-C.
  2017
  A process for increasing growth of hydroponic grown plants
  Taiwan patent application
  106129830
Hwang, H.-H., Wang, C.-H., and Yen, H.-C.
  2018
  A process for increasing growth of hydroponic grown plants under salt stress
  Taiwan patent
  I624544
Hwang, H.-H., and Lu, Y.
  2016
  Increasing frequency of obtaining transgenic plants by the AtRab8B gene
  Taiwan patent
  I550087
Hwang, H.-H., and Wu, E. T.
  2015
  A novel Agrobacterium tumefaciens 1D1460 strain and its application for generating transgenic plants
  Taiwan patent
  I510617
Hwang, H.-H., Tsai, Y.L., and Lai, E.M.
  2015
  A process for increasing efficiency of Agrobacterium-mediated plant transformation
  Taiwan patent
  I488967
Hwang, H.-H., and Wu, E. T.
  2014
  A novel Agrobacterium tumefaciens strain and its application for generating transgenic plants
  Taiwan patent
  I456056
Hwang, H.-H., and Chang, Y.-R
  2009
  Over Expression of BTI1 Enhances Transformation of Arabidopsis Roots
  Taiwan patent
  I378770