Y. C. Chen, Y. W. Lan, S. M. Huang, C. C. Yen, W. Chen, W. J. Wu, T. Staniczek, K. Y. Chong, and C. M. Chen* 2022/06 Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model,Stem Cell Res. Ther. 13: 235. [IF=8.098; Medicine, Research & Experimental, 27/139=Top 19.4%; Q1]. (SCI)
H. Ou-Yang, S. H. Yang, W. Chen, S. H. Yang, A. Cidem, L. Y. Sung and C.M. Chen*. 2022/04 Cruciform DNA structures act as legible templates for accelerating homologous recombination in transgenic animals.,Int. J. Mol. Sci. 23: 3973. (SCI) [IF=6.208; Biochemisrty & Molecular Biology, 67/298 = 22.5%; Q1]. (SCI)
S. W. Chen, H. J. Lin, S. C. S. Tsai, C. L. Lin, C. Y. Hsu, T. L. Hsieh, C. M. Chen*, and K. H. Chang*. 2022/03 Exposure to air pollutants increases the risk of chronic rhinosinusitis in Taiwan residents.,Toxics 10: 173. [IF= 4.472; Toxicology, 24/94=25.5%; Q2]. (SCI)
C. C. Yen, Y. W. Liu, G. R. L. Chang, Y. W. Lan, Y. T. Kao, S. N. Cheng, W. Chen, and C. M. Chen*. 2022/02 Therapeutic effects of kefir peptides on hemophilia-induced osteoporosis in mice with deficient coagulation factor VIII. ,Front. Cell Dev. Biol. 10: 794198. [IF=6.081; Developmental Biology, 6/39 = 15.3%; Q1]. (SCI)
C. M. Chen, Y.-T. Tung, C.-H. Wei, P.-Y. Lee, L. B. Ware, H.-E. Huang, and W. Chen 2022/01 Aspirin attenuated hyperoxia induced acute respiratory distress syndrome (ARDS) through suppressing pulmonary inflammation via NF-κB and MAPKs signaling pathway,Front. Pharmacol. 12: 793107. [IF=5.988; Oncology, 46/351 = 12.7%; Q1]. (SCI)
H. C. Fan, F. W. Chang, J. D. Tsai, K. M. Lin, C. M. Chen, S. Z. Lin, C. A. Liu, and H. J. Harn*. 2021/12 Telomeres and cancer. ,Life 11(12): 1405. [IF= 3.817; Biology, 27/93 = 29%; Q2]. (SCI)
H. C. Fan#, F. W. Chang, Y. R. Pan, S. I. Yu, K. H. Chang, C. M. Chen#, and C. A. Liu*. 2021/11 Approach to the connection between meconium consistency and adverse neonatal outcomes: A retrospective clinical review and prospective in vitro study.,Children 8: 1082. [IF= 2.863; Pediatrics, 40/129 = 31%; Q2]. (SCI)
C. H. Ko, Y. W. Lan, Y. C. Chen, T. T. Cheng, S. F. Yu, A. Cidem, Y. H. Liu, C. W. Kuo, C. C. Yen, W. Chen, and C. M. Chen*. 2021/10 Effects of mean artery pressure and blood pH on survival rate of patients with acute kidney injury combined with acute hypoxic respiratory failure: A retrospective study.,Medicina 57: 1243. [IF=2.430; Medicine, General & Internal, 80/169 = 47.3%; Q2]. (SCI)
Y. T. Kao, Y. T. Chen, H. C. Fan, T. C. Tsai, S. N. Cheng, P. S. Lai, J. K. Chen, and C. M. Chen*. 2021/09 Novel coagulation FVIII gene therapy in a mouse model of hemophilia A by lipid-coated Fe3O4 nanoparticles.,Biomedicines 9: 1116. [IF=4.757; Pharmacology & Pharmacy, 86/279 = Top31.9%; Q2]. (SCI)
H. C. Tsai, C. Sheng, L. S. Chang, Z. H. Wen, C. Y. Ho, and C. M. Chen*. 2021/09 Chitosan-microencapsulated rhEGF in promoting wound healing.,J. Wound Care 30(9): 2-13. [IF=2.066; Dermatology, 46/68 = 67.6%]. (SCI)
Y. W. Chiang, S. W. Wu, C. W. Luo, S. P. Chen, C. J. Chen, W. Y. Chen, C. C. Chang, C. M. Chen*, Y. H. Kuan* 2021/09 Air pollutant particles, PM2.5, exposure and glaucoma in patients with diabetes: A national population-based nested case–control study,Int. J. Environ. Res. Public Health 18(18): 9939. [IF=4.614; Public, Environmental & Occupational Health, 87/230 = Top 30.8%; Q2]. (SCI)
J. L. Wang, Y. T. Tsai, C. H. Lin, A. Cidem, T. Staniczek, G. R. L. Chang, C. C. Yen, W. Chen, K. Y. Chong, and C. M. Chen* 2021/08 Benefits of metformin combined with pemetrexed as a first-line therapy for advanced lung adenocarcinoma patients with diabetes,Biomolecules 11: 1252. [IF=6.064; Biochemistry & Molecular Biology, 75/296 =25.3%; Q2]. (SCI)
J. L. Wang, Y. W. Lan, Y. T. Tsai, Y. C. Chen, T. Staniczek, Y. A. Tsou, C. C. Yen, C. M. Chen* 2021/06 Additive antiproliferative and antiangiogenic effects of metformin and pemetrexed in a non-small-cell lung cancer xenograft model,Front. Cell Dev. Biol. 9: 688062. (SCI) [IF=6.081; Developmental Biology, 6/39 = Top 15.4%; Q1]. (SCI)
H. L. Chen, Y. T. Tung, M. Y. Tu, M. N. Y. Chan, H. S. Wu, C. C. Yen, and C. M. Chen*. 2021/06 Kefir peptides exhibit antidepressant-like activity in mice through the BDNF/TrkB pathway.,J. Dairy Sci. 104(6): 6415-6430. (SCI) [IF=4.225; Agriculture, Dairy & Animal Science,6/62= Top 9.6%; Q1]. (SCI)
M. Y. Tu, K. Y. Han, Y. W. Lan, K. Y. Chang, C. W. Lai, H. L. Chen, C. F. Chen, J. C. Lai, and C. M. Chen*. 2021/06 Association of TGF-β1 and IL-10 gene polymorphisms with osteoporosis in a study of Taiwanese osteoporotic patients ,Genes 12(6): 930. (SCI) [IF=4.141; Genetics & Heredity, 78/191 = 40.8%; Q2]. (SCI)
H. L. Chen, Y. T. Tung, M. Y. Tu, M. N. Y. Chan, H. S. Wu, C. C. Yen, and C. M. Chen*. 2021/06 Effects of kefir peptides on amelioration of depressive-like behavior through BDNF/TrkB pathway in mice. ,J. Dairy Sci. 104(6): 6415-6430. [IF=4.034; Agriculture, Dairy & Animal Science,6/63= Top 9.5%; Q1]. (SCI)
Y. W. Lan, C. M. Chen, and K. Y. Chong 2021/05 In vitro methods to evaluate the effects of mesenchymal stem cells on TGF-β1-induced pulmonary fibrosis,Methods Mol. Biol. (Clifton, N.J.) 2269:83-92. [IF=10.71; Molecular Biology; Q1]. (SCI)
I. O. Yusuf, H. M. Chen, P. H. Cheng, C. Y. Chang, S. J. Tsai, J. I. Chuang, C. C. Wu, B. M. Huang, H. S. Sun, C. M. Chen and S. H. Yang* 2021/05 Fibroblast growth factor 9 stimulates neuronal length through NF-kB signaling in striatal cell Huntington’s disease models,Mol. Neurobiol. 58(5):2396-2406. (SCI) [IF=5.687; Physiology, 7/81 = Top 8.6%; Q1]. (SCI)
C. H. Kuo#, J. Y. Chen#, C. M. Chen#, C. W. Huang, and Y. M. Liou* 2021/03 Effects of varying gelatin coating concentrations on RANKL induced osteoclastogenesis,Exp. Cell Res. 400: 112509. (SCI) [IF=4.145; Oncology, 127/245= 51.8%; Q2] #Co-first authors. (SCI)
Y. W. Chiang, C. H. Su, H. Y. Sun, S. P. Chen, C. J. Chen, W. Y. Chen, C. C. Chang, C. M. Chen, Y. H. Kuan*. 2021/02 Bisphenol A induced apoptosis via oxidative stress generation involved Nrf2/HO-1 pathway and mitochondrial dependent pathways in human retinal pigment epithelium (ARPE-19) cells.,Environ. Toxicol. 2021: 1-11. [IF=4.109; Water Resource, 29/100 = Top 29%; Q2]. (SCI)
F.J. Cheng, C.H. Chen, W.C. Tsai, B.W. Wang, M.C. Yu, T.C. Hsia, Y.L. Wei, Y.C. Hsiao, D.W. Hu, C.Y. Ho, T.S. Li, C.Y. Wu, W.Y. Chou, Y.L. Yu, C.H. Tang, C.Y. Chen, C. M. Chen, ... W.C. Hung*. 2021/02 Cigarette smoke-induced LKB1/AMPK pathway deficiency reduces EGFR TKI sensitivity in NSCLC,Oncogene 40:1162–1175. (SCI) [IF=9.867; Oncology, 30/242= Top 12.4%; Q1]. (SCI)
Y. A. Tsou, W. C. Chang, C. D. Lin, R. L. Chang, M. H. Tsai, L. C. Shih, T. Staniczek, T. F. Wu, H. Y. Hsu, W. D. Chang, C. H. Lai, and C. M. Chen* 2021/02 Metformin increases survival in hypopharyngeal cancer patients with diabetes mellitus: Retrospective cohort study and cell-based analysis,Pharmaceuticals 14: 191. (SCI) [IF=5.215; Pharmacology & Pharmacy, 87/361 = Top24%; Q1]. (SCI)
H. Ou-Yang, S. C. Wu, L. Y. Sung, S. H. Yang, S. H. Yang, K. Y. Chong, and C.M. Chen* 2021/01 STAT3 is an upstream regulator of granzyme g in the maternal-to-zygotic transition of mouse embryos,Int. J. Mol. Sci. 22: 460. (SCI) [IF=6.208; Biochemisrty & Molecular Biology, 67/298 = Top 22.5%; Q1]. (SCI)
G. R. L. Chang, M. Y. Tu, K. Y. Chang, C. F. Chen, J. C. Lai, Y. T. Tung, H. L. Chen, H. C. Fan, and C. M. Chen* 2021 KFP-1, a novel calcium-binding peptide isolated from kefir, promotes calcium influx through TRPV6 channels,Mol. Nutr. Food Res. 2021: 2100182. [IF=6.575; Food Science & Technology, 21/143 = Top 14.7%; Q1] [獲登為當期封面Cover Story; 2021/12/01]. (SCI)
C. F. Chen, H. P. Lee, Y. H. Chao, M. Y. Tu, C. C. Yen, S. H. Yang, C. C. Lin, K. Y. Chong, and C. M. Chen* 2021 Suppression of dendritic cell maturation by kefir peptides alleviates collagen-induced arthritis in mice,Front. Pharmacol. 12: 721594. [IF=5.988; Oncology, 46/351 = 12.7%; Q1]. (SCI)
L. K. Tsai, H. Ou-Yang, J. Xu, C. M. Chen, W. F. Chang, L. Y. Sung* 2021 Somatic cell nuclear transfer in embryonic development and stem cell research,Int. J. Mol. Sci. Submitted Jun., 28, 2021. (SCI) [IF=5.923; Biochemisrty & Molecular Biology, 67/298 = 22.5%; Q1]. (SCI)
I. O. Yusuf, H. M. Chen, P. H. Cheng, C. Y. Chang, S. J. Tsai, J. I. Chuang, C. C. Wu, B. M. Huang, H. S. Sun, C. M. Chen and S. H. Yang* 2021 FGF9 induces neurite outgrowth upon ERK signaling in knock-in striatal Huntington's disease cells,Life Sci. 267:118952. (SCI) [IF=6.780; Pharmacology & Pharmacy, 36/279=Top 12.9%; Q1]. (SCI)
M. C. Tung, Y. W. Lan, H. H. Li, H. L. Chen, S. Y. Chen, Y. H. Chen, C. C. Lin, M. Y. Tu, and C. M. Chen*. 2020 Kefir peptides alleviate high-fat diet-induced atherosclerosis by attenuating macrophage accumulation and oxidative stress in ApoE knockout mice,Scientific Reports 10: 8802. (SCI) [IF=4.379; Multidisciplinary Sciences, 19/126 = Top 15%; Q1] [Nature系列期刊]. (SCI)
R. Reisz*, A. LeBlanc, H. Maddin, T. Dudgeon, D. Scott, T. Huang, J. Chen, C. M. Chen, and S. Zhong. 2020 Early Jurassic dinosaur fetal dental development and its significance for the evolution of sauropod dentition, Nature Communications. 11: 2240. (SCI) [IF=14.919; Multidisciplinary Sciences, 5/126=Top 3.9%; Q1] [Nature系列期刊] [Science.Carleton.Ca 特別報導; 2020/5/7]. (SCI)
C. M. Chen, Y. T. Tung, C. H. Wei, P. Y. Lee, and W. Chen*. 2020 Anti-inflammatory and reactive oxygen species suppression through aspirin pretreatment to treat hyperoxia-induced acute lung injury in NF-κB–luciferase inducible transgenic mice,Antioxidants 9(5): 429. (SCI) [IF=6.312; Food Sciences & Technology, 11/144 = Top 7.6%; Q1]. (SCI)
Y. H. Chen, H. L. Chen, H. C. Fang, Y. T. Tung, C. W. Kuo, M. Y. Tu, and C. M. Chen*. 2020 Anti-inflammatory, antioxidant, and antifibrotic effects of kefir peptides on salt-induced renal vascular damage and dysfunction in aged stroke-prone spontaneously hypertensive rats ,Antioxidants 9(9): 790. (SCI) [IF=6.312; Food Sciences & Technology, 11/144 = Top 7.6%; Q1]. (SCI)
M. Y. Tu, H. Chu, Y. J. Lin, K. T. Chiang, C. M. Chen, C. S. Yang, and C. Y. Lai*. 2020 Combined effect of heart rate responses and anti-G straining manoeuvre effectiveness on G tolerance in a human centrifuge ,Scientific Reports 10:21611. (SCI) [IF=4.379; Multidisciplinary Sciences, 19/126 = Top 15%; Q1] [Nature系列期刊]. (SCI)
C. M. Chen, H. C. Lu, Y. T. Tung, and W. Chen*. 2020 Antiplatelet therapy for acute respiratory distress syndrome,Biomedicines 8:230. (SCI) [IF=6.081; Pharmacology & Pharmacy, 32/275= Top11.6%; Q1]. (SCI)
M. Y. Tu, K. Y. Han, G. R. L. Chang, G. D. Lai, K. Y. Chang, C. F. Chen, J. C. Lai, C. Y. Lai, H. L. Chen, and C. M. Chen*. 2020 Kefir peptides prevent estrogen deficiency-induced bone loss and modulate the structure of the gut microbiota in ovariectomized mice ,Nutrients 12:3432. (SCI) [IF=5.717; Nutrition & Diebetics, 17/89 = Top 19.1%; Q1]. (SCI)
C. C. Yen, W. H. Chang, M. C. Tung, H. L. Chen, H. C. Liu, C. H. Liao, Y. W. Lan, K. Y. Chong, S. H. Yang, and C. M. Chen*. 2020 Lactoferrin protects hyperoxia-induced lung and kidney systemic inflammation from in an in vivo imaging model of NF-κB/luciferase transgenic mice ,Mol. Imaging Biol. 22(3):526-538. (SCI) [IF=3.488; Radiology, Nuclear Medicine & Medical Imaging, 35/186 =18.8%c; Q1]. (SCI)
H. L. Chen, K.F. Hung, C. C. Yen, C. H. Laio, J. L. Wang, Y. W. Lan, K. Y. Chong, H. C. Fan, and C. M. Chen*. 2019/09 Kefir peptides alleviate particulate matter <4 μm (PM4.0)-induced pulmonary inflammation by inhibiting the NF-κB pathway using luciferase transgenic mice,Scientific Reports 9: 11529. (SCI) [IF=5.097; Multidisciplinary Sciences, 19/126 = Top 15%; Q1] [Nature系列期刊]. (SCI)
Y. A. Tsou, W. D. Chang, J. J. Lu, T. F. Wu, H. L. Chen, C. M. Chen, and M. H. Tsai*. 2019/09 The effect of metformin use on hypopharyngeal squamous cell carcinoma in diabetes mellitus patients,BMC Cancer 19: 862. (SCI) [IF=4.430; Oncology, 121/308= 39.3%; Q2]. (SCI)
T. T. Huang, Y. W. Lan, W. H. C. M. Chen, Y. F. Ko, D. Ojcius, J. Martel, J. Young and K. Y. Chong*. 2019/08 Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells ,Scientific Reports 9: 5145. [IF=5.097; Multidisciplinary Sciences, 19/126 = Top 15%; Q1] [Nature系列期刊]. (SCI)
S. W. Tsai, H. S. Wu, I. A. Chen, H. L. Chen, G. R. L. Chang, H. C. Fan*, and C. M. Chen*. 2019/07 A mutant-type porcine myostatin propeptide (D75A-MSPP) elevates myoblast growth and differentiation in C2C12 cells and in high fat diet-fed mice ,Res. Vet. Sci. 124: 200-211. (SCI) [IF=2.534; Veterinary Sciences, 20/166 = Top 12%; Q1]. (SCI)
H.C. Tsai, G. R. L. Chang, H. C. Fan, H. Ou-Yang, L. C. Huang, S. C. Wu, and C.M. Chen*. 2019/06 A mini-pig model for evaluating the efficacy of autologous platelet patches on induced acute full thickness wound healing ,BMC Vet. Res. 15: 191. (SCI) [IF=2.741; Veterinary Sciences, 16/166 = Top 9.6%; Q1]. (SCI)
C. F. Tu, C. K. Chuang, K. S. Hsiao, C. H. Chen, C. M. Chen, S. H. Peng, Y. H Su, M. T. Chiou, C. H. Yen, S. W. Hung, T. S. Yang, and C.M. Chen. 2019/05 Lessening of porcine epidemic diarrhoea virus susceptibility in piglets after editing of the CMP-N-glycolylneuraminic acid hydroxylase gene with CRISPR/Cas9 to nullify N-glycolylneuraminic acid expression ,PLoS ONE 14(5): 0217236. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
H.C. Tsai, C. W. Lehman, C. C. Lin, S. W. Tsai, and C.M. Chen*. 2019/04 Functional evaluation for adequacy of MDCK-lineage cells in influenza research ,BMC Res. Notes 12: 101. (SCI) IF=1.66. (SCI)
Y. W. Lan, J. C. Yang, C. C. Yen, T. T. Huang, Y. C. Chen, H. L. Chen, K. Y. Chong, and C. M. Chen*. 2019/01 Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema,Stem Cell Res. Ther. 10(1): 163. (SCI) [IF=6.832; Medicine, Research & Experimental, 31/186=Top 16.7%; Q1]. (SCI)
H.C. Tsai, C. W. Lehman, and C.M. Chen*. 2019/01 Use of platelet-rich plasma and platelet-derived patches to treat chronic wounds,J. Wound Care. 28(1):15-21. (SCI) [IF=2.072; Dermatology, 42/89=47.2%; Q2] . (SCI)
H.C. Fan, C.M. Chen, C.S. Chi, J.D. Tsai, K. L. Chiang, Y.K. Chang, S.Z. Lin, and H.J. Harn*. 2019/01 Targeting telomerase and ATRX to induce tumor senescence and apoptosis in malignant gliomas, Int. J. Mol. Sci. 20(1): 200. (SCI) [IF=5.923; Biochemisrty & Molecular Biology, 67/298 = 22.5%; Q1]. (SCI)
C. C. Kao, H. L. Chen, M. Y. Tu, and C. M. Chen*. 2019/01 Serum and urinary SOD3 in patients with type 2 diabetes: comparison with early chronic kidney disease patients and association with development of diabetic nephropathy ,Am. J. Physiol. Renal Physiol. 316(1): F32-F41. (SCI) [IF=3.377; Urology & Nephrology, 25/118 = Top 21.2%; Q1]. (SCI)
H.C. Tsai*, H. C. Shu, L. C. Huang, and C.M. Chen* 2019 A randomized clinical trial comparing a collagen-based composite dressing versus topical antibiotic ointment on healing full-thickness skin wounds to promote epithelialization,Formosan J. Surgery 52: 52-56. (SCI) [IF=0.25; Surgery, 256/270 = 94.8%;Q4]. (SCI)
T. T. Huang, Y. W. Lan, Y. F. Ko, C. M. Chen, H. C. Lai, D. M. Ojcius, J. Martel, J. D. Young, and K. Y. Chong*. 2018/09 Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway ,J. Ethnopharmacol. 220: 239-249. (SCI) [IF=4.360; Integrative & Complementary Medicine, 4/39 = Top 10.2%; Q1]. (SCI)
Y. T. Wang, H. C. Liu, H. C. Chen, Y. C. Lee, T. C. Tsai, H. L. Chen, H. C. Fan, and C.M. Chen*. 2018/07 Oral immunotherapy with the ingestion of house dust mite extract in a murine model of allergic asthma ,Allergy Asthma Clin. Immunol. 14: e43. (SCI) [IF=2.104; Allergy, 19/27 = 70.3%; Q3]. (SCI)
C. Y. Tu, F. J. Cheng, C. M. Chen*, S. L. Wang, Y. C. Hsiao, C. H. Chen, T. C. Hsia, Y. H. He, B. W. Wang, I. S. Hsieh, Y. L. Yeh, C. H. Tang, Y. J. Chen, and W. C. Huang. 2018/05 Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs ,Mol. Oncol. 12(5): 705-723. (SCI) [IF=6.603; Oncology, 38/308= Top 12.3%; Q1]. (SCI)
W. J. Lo, C. L. Lin, Y. C. Chang, L. Y. Bai, C. Y. Lin, J. A. Liang, L. Y. Li, L. M. Chao, C. F. Chiu, C. M. Chen*, and S. P. Yeh. 2018/04 Total body irradiation tremendously impair the proliferation, differentiation and chromosomal integrity of bone marrow-derived mesenchymal stromal stem cells,Ann. Hematol. 97(4): 697-707. (SCI) [IF=3.673; Hematology, 40/93 = 43%; Q2]. (SCI)
Y. T. Tung, H. L. Chen, H. S. Wu, M. H. Ho, K. Y. Chong, and C. M. Chen*. 2018/03 Kefir peptides prevent hyperlipidemia and obesity in high fat diet-induced obese rats via lipid metabolism modulation,Mol. Nutri. Food Res. 62(3): 1700505. (SCI) [IF=5.914; Food Science & Technology, 9/160= Top 5.6%; Q1] . (SCI)
C. Y. Tu†, C. M. Chen†, W. C. Liao, B. R. Wu, C. Y. Chen, W. C. Chen, T. C. Hsia, W. C. Cheng, and C. H. Chen*. 2018 Comparison of the effects of the three major tyrosine kinase inhibitors as first-line therapy for non-small-cell lung cancer harboring epidermal growth factor receptor mutations,Oncotarget. 9(36): 24237-24247. (SCI) [5-y IF=5.168; Oncology, 44/217= Top 20.3%; Q1] †Co-first author.. (SCI)
C. Y. Tu, B. W. Wang, F. J. Cheng, C. H. Chen, T. C. Hsia, Y. L. Wei, C. Y. Chen, I. S. Hsieh, Y. L. Yeh, L. Y. Wang, C. M. Chen, W. C. Chang and W. C. Chang*. 2018 Incense burning smoke sensitizes lung cancer cells to EGFR TKI by inducing AREG expression ,Am. J. Cancer Res. 8(12):2575-2589. (SCI) [IF=6.166; Oncology, 70/308 = 22.7%; Q1]. (SCI)
Y. A. Tsou, M. C. Tung, K. A. Alexander, W. D. Chang, M. H. Tsai, H. L. Chen, and C. M. Chen*. 2018 The role of BPIFA1 in upper airway microbial infections and correlated diseases,BioMed. Res. Int. 2018: e2021890. (SCI) [IF=3.411; Biotechnology & Applied Microbiology, 69/159 = 43.4%; Q2]. (SCI)
C.M. Chen*, J. L. Wang, Y. T. Tsai, J. H. Jiang, and H. L. Chen. 2017/09 Repurposing of metformin and lung cancer management. In: A Global Scientific Vision - Prevention, Diagnosis, and Treatment of Lung Cance, InTech Publishers, Inc. Rijeka, EU. Chapter 9, pp. 149-163. ISBN978-953-51-5119-7..
L. S. Her, S. H. Mao, C. Y. Chang, P. H. Cheng, H. I. Yang, C. M. Chen and S. H. Yang*. 2017/09 miR-196a enhances neuronal morphology through suppressing RANBP10 to provide neuroprotection in Huntington's disease,Theranostics. 7(9): 2452-2462. (SCI) [IF=11.556; Medicine, Research & Experimental, 6/186 = Top 3.2%; Q1]. (SCI)
Y. W. Lan, S. M. Theng, T. T. Huang, K. B. Choo, C. M. Chen, H. P. Kuo, and K. Y. Chong*. 2017/08 Oncostatin M-preconditioned mesenchymal stem cells alleviate bleomycin-induced pulmonary fibrosis through paracrine effects of the hepatocyte growth factor,Stem Cells Translat. Med. 6(3): 1006-1017. (SCI) [IF=6.940; Cell & Tissue Engineering, 4/31= 12.9%; Q1]. (SCI)
C. W. Lai, H. L. Chen, K. Y. Chong, W. Y. Lin, and C. M. Chen*. 2017/05 A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice,Oncotarget. 8(5): 7357-7369. (SCI) [IF=5.168; Oncology, 44/217= Top 20.3%; Q1]. (SCI)
Y. A. Tsou, Y. T. Tung, H. C. Chen, T. F. Wu, C. C. Lin, C. H. Lai, H. L. Chen, and C. M. Chen*. 2017/03 Lactoferrin interacts with SPLUNC1 to attenuate lipopolysaccharide-induced inflammation of human nasal epithelial cells via down-regulated MEK1/2-MAPK signaling,Biochem. Cell Biol. 95(3): 394-399. [IF=3.626; Biochemistry & Molecular Biology, 168/298= 56.4%; Q3] (SCI). (SCI)
J. Y. Hsu, Y. L. Jhang, P. H. Cheng, Y. F. Chang, S. H. Mao, H. I. Yang, C. W. Lin, C. M. Chen and S. H. Yang*. 2017 The truncated C-terminal fragment of mutant ATXN3 disrupts mitochondria dynamics in Spinocerebellar ataxia type 3 models,Front. Mol. Neurosci. 10: 196. eCollection 2017. (SCI) [IF=5.639; Neurosciences, 60/273 = Top 21.9%; Q1]. (SCI)
P. H. Cheng, Y. F. Chang, S. H. Mao, H. L. Lin, C. M. Chen, and S. H. Yang*. 2016/08 Lentiviral transgenesis in mice via a simple method of viral concentration,Theriogenology 86(6): 1427-1435. (SCI) [IF=2.740; Veterinary Sciences, 22/166 = Top 13.3%; Q1]. (SCI)
C. W. Lai, H. L. Chen, T. C. Tsai, T. W. Chu, S. H. Yang, K. Y. Chong, and C. M. Chen*. 2016/08 Sexually dimorphic expression of eGFP transgene in the Akr1A1 locus of mouse liver regulated by sex hormone-related epigenetic remodeling,Scientific Reports 6: e24023. [IF=4.379; Multidisciplinary Sciences, 19/126 = Top 15%; Q1] [Nature系列期刊]. (SCI)
C. W. Lai, H. L. Chen, C. C. Yen, J. L. Wang, S. H. Yang, and C. M. Chen*. 2016/06 Using dual-fluorescence reporting genes to establish an in vivo imaging model of orthotopic lung adenocarcinoma in mice,Mol. Imaging Biol. 18(6): 849-859. [IF=3.488; Radiology, Nuclear Medicine & Medical Imaging, 35/186 = 18.8%; Q1]. (SCI)
W. J. Lo, W. S. Chang, H. F. Hsu, H. X. Ji, C. L. Hsiao, C. W. Tsai, S. P. Yeh, C. M. Chen* and D. T. Bau*. 2016/05 Significant association of interleukin-10 polymorphisms with childhood leukemia susceptibility in Taiwan,In Vivo 30(3): 265-269. (SCI) [Medicne, Research & Experimental]. (SCI)
S. W. Tsai, H. L. Chen, Y. T. Tung, S. H. Yang, C. Y. Liu, M. Lu, H. J. Pai, C. C. Lin, and C. M. Chen*. 2016/01 Myostatin propeptide gene delivery by gene gun ameliorates muscle atrophy in a rat model of botulinum toxin-induced nerve denervation,Life Sci. 146: 15-23. (SCI) [IF=5.037; Life Science, 35/186 = Top 2.7%; Q1]. (SCI)
H. L. Chen, T. C. Tsai, Y. C. Tsai, J. W. Liao, C. C. Yen, and C. M. Chen*. 2016 Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway,Nutrition & Diabetes 6(12): e237. (SCI) [IF=5.097; Internal Medicine, 21/146= 15.4%; Q1] [Nature系列期刊]. (SCI)
W. Chen, Y. Y. Chen, C. F. Tsai, S. C. C. Chen, M. S. Lin, L. B. Ware, and C. M. Chen*. 2015/09 Incidence and outcomes of acute respiratory distress syndrome–A nationwide registry based study in Taiwan, 1997-2011, Medicine 94(43): e1849. [IF=1.889; Medicine, General & Internal, 105/313= Top 33.5%; Q2]. (SCI)
M. H. Fu, C. L. Li, H. L. Lin, S. J. Tsai, Y. Y. Lai, Y. F. Chang, P. H. Cheng, C. M. Chen, and S. H. Yang*. 2015/09 The potential regulatory mechanisms of miR-196a in Huntington's disease through bioinformatic analyses, PLoS ONE 10(9): e0137637. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
C. Y. Liu, M. L. Lee, C. S. Yang, C. M. Chen, M. Y. Min, and H.W. Yang*. 2015/08 Morphological and physiological evidence of a synaptic connection between the lateral parabrachial nucleus and neurons in the A7 catecholamine cell group in rats,J. Biomed. Sci., 22(1): 79. [IF=8.410; Medicine, General & Internal,38/195 =19.5%; Q1]. (SCI)
Y. W. Lan, K. B. Choo, C. M. Chen, T. H. Hung, Y. B. Chen, C. H. Hsieh, H. P. Kuo, and K. Y. Chong*. 2015/06 Hypoxia-preconditioned mesenchymal stem cells attenuates bleomycin-induced pulmonary fibrosis,Stem Cell Res. Ther. 6(1): 97. (SCI) [IF=4.963; Medicine, Research & Experimental, 19/133=Top 14.3%; Q1] (Highly Access Paper: 2063 times) [Cell Research & Therapy 6:130, 2015特別報導; 07/14/2015]. (SCI)
C. W. Kuo, C. J. Shen, Y. T. Tung, H. L. Chen, Y. H. Chen, W. H. Chang, K. C. Cheng, S. H. Yang, and C. M. Chen*. 2015/06 Extracellular superoxide dismutase ameliorates streptozotocin-induced diabetic nephropathy via inhibiting the ROS/ERK1/2 signaling, Life Sci. 135: 77-86. (SCI) [IF=5.037; Medicine, Research & Experimental, 35/186=18.8%; Q1]. (SCI)
Y. A. Tsou, C. D. Lin, H. H. Hsu, M. T. Peng, Y. K. Kuo, N. Tien, J. P. Li, C. K. Wang, H. S. Wu, M. H. Tsai, C. M. Chen* and C. H. Lai. 2015/06 Association of beta-lactam-sensitive Haemophilus influenzae type B with adenoid biofilm formation in patients with adenoidectomy surgery,Surg. Infect. 16(6): 709-715. (SCI) [IF=2.150; Surgery 120/270= 44.4%; Q2] [Feature Articles 特別報導; 12/08-22/2015]. (SCI)
Y. T. Tung, P. W. Huang, Y. C. Chou, C. W. Lai, H. P. Wang, H. C. Ho, C. C. Yen, C. Y. Tu, D. C. Yeh, J. L. Wang, K. Y. Chong, and C. M. Chen* 2015/05 Lung tumorigenesis induced by human vascular endothelial growth factor (hVEGF)-A165 overexpression in transgenic mice and amelioration of tumor formation by miR-16,Oncotarget. 6(12): 10222-10238. (SCI) [IF=5.168; Oncology, 44/217= Top 20.3%; Q1]. (SCI)
T. C. Tsai, Y. T. Tung, Y. H. Kuo, J. W. Liao, H. C. Tsai, K. Y. Chong, H. L. Chen, and C. M. Chen* 2015/02 Anti-inflammatory effects of Antrodia camphorata, an herbal medicine, in a mouse skin ischemia model,J. Ethnopharmacol. 159: 113-121. (SCI) [IF=4.360, Integrative & complementary medicine, 4/39= Top 10.2%; Q1]. (SCI)
K. Y. Chong, C. J. Hsu, T. H. Hung, H. S. Hu, T. H. Wang, C. H. Wang, C. M. Chen, K. B. Choo, H. C. Lai, and C. P. Tseng. 2015/01 Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells,Cancer Biol Ther. 16(1): 149-159. (SCI) [IF=4.742, Oncology, 102/308=33.1%; Q2]. (SCI)
H. C. Liu, M. C. Lu, Y. C. Lin, Y. C. Lai, M. S. Jan, W. L. Lin, and C. M. Chen* 2015/01 Aortic graft infection caused by invasive pulmonary aspergillosis,Surg. Infect. 16(1): 112-113. (SCI) [IF=2.150; Surgical, 120/270=44.4%; Q2]. (SCI)
H. L. Chen, Y. T. Tung, C. H. Chuang, M. Y. Tu, T. C. Tsai, S. Y. Chang, and C. M. Chen* 2015/01 Kefir improves bone mass and microarchitecture in an ovariectomized rat model of postmenopausal osteoporosis,Osteoporosis Int. 26: 589-599. (SCI) [IF=4.507; Endocrinology & Metabolism, 47/177= 26.6%; Q2] [World Biomedical Frontiers特別報導; 09/28/2015]. (SCI)
H. C. Liu, H. L. Chen, and C.M. Chen*. 2015/01 House dust mite allergy and associated allergen-specific immunotherapy in allergic asthma,Immunome Res. 11: 085. (SCI) [Unofficial IF*=19.87; Immunology]. (SCI)
Y. A. Tsou, C. C. Lin, C. J. Tai, M. H. Tsai, C. M. Chen*, and C. H. Lai*. 2015 Interleukin-13 inhibits lipopolysaccharide-induced BPIFA1 expression in nasal epithelial cells ,PLoS ONE 10(12): e0143484. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
M. Y. Tu, H. L. Chen, Y. T. Tung, T. C. Tsai, S. Y. Chang, C. H. Chuang, and C. M. Chen*. 2015 Short-term effects of kefir-fermented milk consumption on bone mineral density and bone metabolism in a randomized clinical trial of osteoporotic patients,PLoS ONE 10(12): e0144231. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
Y. L. Lin, H. L. Chen, S. B. Cheng, D. C. Yeh, C. C. Huang, F. K. P’eng, T. C. Tsai, C. C. Wu and C. M. Chen*. 2015 Methylation-silencing RCC1 expression is associated with tumorigenesis and depth of invasion in gastric cancer,Int. J. Clin. Exp. Pathol. 8(11):14257-14269. (SCI) [IF=1.706; Oncology, 280/308= 90.9%; Q4]. (SCI)
T. H. Hung, Y. H. Li, C. P. Tseng, Y. W. Lan, S. C. Hsu, Y. H. Chen, T. T. Huang, H. C. Lai, C. M. Chen, K. B. Choo, and K. Y. Chong 2015 Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines,Cancer Gene Ther. 22(5):262-270. (SCI) [IF=5.987, Medcine, Research & Experimental, 33/186=17.7%; Q1]. (SCI)
H. L. Chen, Y. T. Tung, C. L. Tsai, C. W. Lai, H. C. Tsai, Y. L. Lin, C. H. Wang, and C.M. Chen 2014/09 Kefir improves fatty liver syndrome through inhibited lipogenesis pathway in leptin-deficient ob/ob knockout mice,Int. J. Obesity 38(9): 1172-1179. (SCI) [IF=5.095; Nutrition & Dietetics,15/103= Top 14.6%; Q1] [Nature系列期刊]. (SCI)
T. H. Hung, C. M. Chen, C. P. Tseng, C. J. Shen, H. L. Wang, K. B. Choo, and K. Y. Chong 2014/08 FZD1 activates protein kinase C delta-mediated drug-resistance in multidrug-resistant MES-SA/Dx5 cancer cells, Int. J. Biochem. Cell Biol. 53: 55-65. (SCI) [IF=5.085; Biochemistry & Molecular Biology 88/298= 29.5%; Q2]. (SCI)
H. C. Liu, S. Y. Pai, H. L. Chen, C. W. Lai, T. C. Tsai, W.T.K. Cheng, S. H. Yang, and C. M. Chen* 2014/07 Recombinant Derp5 secreted in the milk leading by aS1-casein signal peptide protects against dust mite allergen-induced airway inflammation ,J. Dairy Sci. 97: 6792-6803. (SCI) [IF=4.034; Agriculture, Dairy & Animal Science, 6/63 = Top 9.5%]. (SCI)
Y. T. Tung, T. Y. Tang, H. L. Chen, S. H. Yang, K. Y. Chong, and C.M. Chen 2014/06 Lactoferrin protects against chemical-induced rat liver fibrosis through inhibiting stellate cells activation,J. Dairy Sci. 97(6): 3281-3291. (SCI) [IF=4.034; Agriculture, Dairy & Animal Science, 6/63 = Top 9.5%; Q1]. (SCI)
C. C. Lin*, H. H. Chen, Y. K. Chen, H. C. Chang, P. Y. Lin, I. H. Pan, D. Y. Chen, C. M. Chen, and S. Y. Lin 2014/06 Rice bran feruloylated oligosaccharides activate dendritic cells via toll-like receptor 2 and 4 signaling,Molecules 19: 5325-5347. (SCI) [IF=4.411; Biotechnology & Applied Microbiology, 69/159 = 38.9%; Q2]. (SCI)
R. H. Lin, C. C. Huang, Y. A. Tsou*, C. D. Lin, M. H. Tsai, J. H. Chen, C. M. Chen* and Y. T. Shiao 2014/06 Correlation between imaging characteristics and microbiology in patients with deep neck infections: A retrospective review of one hundred sixty-one cases ,Surg. Infect. 15(6): 794-799. (SCI) [IF=2.150; Surgery 120/270= 44.4%; Q2]. (SCI)
Z. L. Lai, Y. A. Tsou, S. R. Fan, M. H. Tsai, H. L. Chen, J. C. Cheng, and C. M. Chen* 2014/06 Methylation-associated gene silencing of RARB in Areca arcinogens-induced mouse oral squamous cell carcinoma,BioMed. Res. Int. 2014: e378358. (SCI) [IF=3.411; Biotechnology & Applied Microbiology, 69/159 = 43.4%; Q2]. (SCI)
Y. J. Chen, M. S. Lin, K. Y. Hsu, C. R. Chen, C.M. Chen, and W. Chen 2014/05 Prevalence of asymptomatic peripheral arterial disease and related risk factors in younger and elderly patients in Taiwan ,Angiology 65(5): 396-401. (SCI) [IF=3.619; Peripheral Vascular Disease, 25/65 = 38.5%; Q2]. (SCI)
Y. A. Tsou, C. C. Lin, C. J. Tai, M. H. Tsai, T. C. Tsai, and C. M. Chen 2014/04 Chronic rhinosinusitis and the risk of nasopharyngeal cancer in a Taiwanese health study,Am. J. Rhinol. Allergy 28(4):168-172. (SCI). [IF=2.467; Otorhinolaryngology 11/58= 19%; Q1] [MDLinx特別報導; 07/28/2014]. (SCI)
H. L. Chen, C. C. Yen, S. M. Wang, T. C. Tsai, Z. L. Lai, J. Y. Sun, W. Lin, W. H. Hsu, and C. M. Chen 2014/03 Aerosolized bovine lactoferrin reduces lung injury and fibrosis in mice exposed to hyperoxia,BioMetals 27: 1057-1068. (SCI) [IF=2.949; Biochemistry & Molecular Biology 201/298= 67.4%; Q3]. (SCI)
C. W. Lai, H. L. Chen, K. Y. Lin, F. C. Liu, K. Y. Chong, W. T. K. Cheng, and C.M. Chen 2014/03 FTSJ2, a heat shock-inducible mitochondrial protein, suppresses cell invasion and migration,PLoS ONE 9(3): e90818. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
Y. A. Tsou, M. T. Peng, Y. F. Wu, C. H. Lai, C. D. Lin, C. J. Tai, M. H. Tsai, C. M. Chen*, and H. C. Chen 2014/02 Decreased PLUNC expression in nasal polyps is associated with multibacterial colonization in chronic rhinosinusitis patients,Eur. Arch. Otorhinolaryngol. 271 (2): 299-304. (SCI) [IF=2.503; Otorhinolaryngology, 14/58= 24.1%; Q1] [Leading News特別報導; 05/07/2013]. (SCI)
L.Y. Sung, W. F. Chang, Q Zhang, C. C. Liu, C. C. Chang, H. Fu, J. Y. Liou, W. T. K. Cheng, M. Okuka, D. L. Keefe, Y. E. Chen, L. Liu, C. M. Chen, and J. Xu* 2014 Telomere elongation and naïve pluripotent stem cells achieved from telomerase haplo-insufficient cells by somatic cell nuclear transfer,Cell Reports. 9: 1603-1609. (SCI) [IF=9.423; Cell Biology, 28/196= Top 14.3%; Q1]. (SCI)
Y. W. Lan, K. B. Choo, C. M. Chen, T. H. Hung, C. H. Hsieh, H. P. Kuo, and K. Y. Chong* 2014 Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway,Oncotarget. 5(23): 12273-12290. (SCI) [5-y IF=5.168; Oncology, 44/217= Top 20.3%; Q1]. (SCI)
Y. T. Tung, T. C. Tsai, Y. H. Kuo, H. L. Chen, C. C. Yen, J. Y. Sun, W. H. Chang, H. L. Chen, and C. M. Chen* 2014 Comparison of solid-state-cultured and wood-cultured Antrodia camphorata in anti-inflammatory effects using NF-κB/luciferase inducible transgenic mice,Phytomedicine 21(2014): 1708-1716. [IF=5.340, Integrative & complementary medicine, 2/39= Top5.1%; Q1]. (SCI)
H. C. Liu, M. C. Lu, Y. C. Lin, T. C. Wu, J. Y. Hsu, M. S. Jan, and C. M. Chen* 2014 Differences in IL-8 in serum and exhaled breath condensate from patients with exacerbated COPD or asthma attacks, J. Formos. Med. Assoc. 113: 908-914. (SCI) [IF=3.282, Medicine, General & Internal,40/313=12.8; Q1]. (SCI)
Y. A. Tsou, H. J. Huang, T. C. Wang, C. M. Chen*, and C. Y. Chen* 2014 Evaluation of correlation of cell cycle proteins and Ki67 interaction in paranasal sinus inverted papilloma prognosis and squamous cell carcinoma transformation,BioMed. Res. Int. 2014: e634945. (SCI) [IF=3.411; Biotechnology & Applied Microbiology, 69/159 = 43.4%; Q2]. (SCI)
C. J. Shen, Y. A. Tsou, S. C. Wu, W. T. K. Cheng, H. L. Chen, C. Y. C. Chen, and C. M. Chen* 2014 Osteoponin promoter controlled by DNA methylation: Aberrant methylation in cloned porcine genome,BioMed. Res. Int. 2014: e327538. (SCI) [IF=3.411; Biochemistry & Molecular Biology, 116/298 = 43.4%; Q2]. (SCI)
J. T. Huang, C. P. Tseng, M. H. Liao, C. H. Lu, W. Z. Yeh, N. Sakamoto,C. M. Chen*, and J. C. Cheng. 2013/09 Hepatitis C virus replication is modulated by the interaction of non-structural protein NS5B and fatty acid synthase, J. Virol. 87(9): 4994-5004. (SCI) [IF=5.103; Virology, 6/36 =16.7%; Q1] [SciBite: Pharma特別報導; 02/26/2013]. (SCI)
W. Chen, J. Y. Chen, H. L. Chen, Y. T. Tung, C. W. Kuo, F. C. Mao, C. H. Chuang, K. Y. Chong, and C.M. Chen* 2013/09 High-frequency ultrasound imaging to evaluate liver fibrosis progression in rats and Yi Guan Jian herbal therapeutic effects,Evid. Complement. Alter. Med. 2013: e302325. (SCI) [IF=2.629, Integrative & complementary medicine, 12/29=41.4%; Q2]. (SCI)
91. S. T. Wen, W. Chen, H. L. Chen, C. W. Lai, C. C. Yen, K. H. Lee, and C.M. Chen* 2013/09 Amniotic fluid stem cells from EGFP transgenic mice attenuate hyperoxia-induced acute lung injury,PLoS ONE 8(9): e75383. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
S. W. Tsai, Y. T. Tung, H. L. Chen, C. J. Shen, C. H. Chuang, T. Y. Tang, and C. M. Chen* 2013/08 Treadmill running upregulates the expression of acetylcholine receptor in rat gastrocnemius following Botulinum Toxin A injection,J. Orthop Res. 31: 125–131. (SCI) [IF=3.494; Orthopedics, 14/117= Top 12%; Q1][Science.gov特別報導; 03/15/2013]. (SCI)
Y. T. Tung, H. L. Chen, C. Y. Lee, Y. C. Chou, P. Y. Lee, H. C. Tsai, C. C. Yen, Y. L. Lin, and C.M. Chen*. 2013/07 Active component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, attenuates lung tumorigenesis via inhibitions of VEGF, Cyclin A and Cyclin B expression,Evid. Complement. Alter. Med. 2013: e319247. [IF=2.629, Integrative & complementary medicine, 12/29=41.4%; Q2]. (SCI)
Y. T. Tung, H. L. Chen, H. C. Tsai, S. H. Yang, Y. C. Chang, and C.M. Chen* 2013/07 Therapeutic potential of andrographolide isolated from the leaves of Andrographis paniculata Nees for treating lung adenocarcinomas,Evid. Complement. Alter. Med. 2013: e305898. [IF=2.629, Integrative & complementary medicine, 12/29=41.4%; Q2]. (SCI)
C. M. Chen*, Z. L. Lai, M. L. Wang, and H. L. Chen 2013/06 Cloning and expression of human extracellular superoxide dismutase (EC-SOD) gene in probiotic Lactobacillus casei,Int. J. Biosci. Biochem. Bioinform. 3(6): 557-561. (SCI). (SCI)
H. L. Chen, T. C. Tsai, J. C. Huang, D. C. Wang, and C.M. Chen* 2013/06 Dimorphic goat amelogenin alleles on sex chromosomes for gender determination of preimplantation embryos, Int. J. Biosci. Biochem. Bioinform. 3(6): 619-623. (SCI). (SCI)
Y. A. Tsou, C. C. Lin, C. H. Lai, C. Y. Wang, C. D. Lin, P. C. Chen, I. J. Tsai, C. M. Chen, F. C. Sung*, and M. H. Tsai 2013/05 Does Adenotonsillectomy really reduced clinic visits for pediatric upper respiratory tract infections? A national database study in Taiwan,Int. J. Pediatr. Otorhinolaryngol. 77(5): 677-681. (SCI) [IF=1.675; Otorhino- laryngology, 28/58=48.3%; Q2]. (SCI)
C. J. Shen, C. C. Lin, P. C. Shen, W. T. K. Cheng, H. L. Chen, T. C. Chang, S. S. Liu, and C. M. Chen* 2013/05 Imprinted genes and satellite are differentially methylated loci in cloned bovine genomes,Cell Reprogram. 15(5):413-24. (SCI) [IF=1.987; Genetics & Heredity, 139/183 =76%; Q4][BioPortfolio: The World's Leading Biotech, Healthcare and Medical Resource特別報導; 11/08/2013]. (SCI)
M. S. Lin, K. Y. Hsu, Y. J. Chen, C. R. Chen, C. M. Chen,and W. Chen* 2013/05 Prevalence and risk factors of asymptomatic peripheral arterial disease in patients with COPD in Taiwan,PLoS ONE 8(5): e64714. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
Y. T. Tung, C. C. Yen, H. L. Chen, P. Y. Lee, H. C. Tsai, M. F. Lin, and C.M. Chen*. 2013/04 Bovine lactoferrin inhibits lung cancer growth through suppression of inflammation and VEGF expression,J. Dairy Sci. 96(4): 2095-2106. (SCI) [IF=4.034; Agriculture, Dairy & Animal Science, 6/63 = Top 9.5%; Q1] [Cancer Commons: Angiogenesis特別報導; 02/22/2013] (HiCi Paper; 8/17/2015). (SCI)
Y. A. Tsou#, C. M. Chen#, T. C. Lin, F. W. Hu, C. J. Tai, H. C. Chen, T. H. Yeh, H. J. Harn, M. H. Tsai, and C. I. Jan* 2013/04 Decreased Splunc-1 expression is associated with Pseudomonas infection in surgical treated chronic rhinosinusitis patients who may require repeated sinus surgery,Laryngoscope 123(4): 845-851. (SCI) [IF=3.325; Otorhinolaryngology, 9/44 = 20.4%; Q1] † Co-first author. (SCI)
P. H. Cheng, C. L. Li, S. J. Tsai, Y. Y. Lai, A. W. S. Chan, C.M. Chen, and S. H. Yang* 2013/02 MiR-196a ameliorates phenotypes of Huntington's disease in cell, transgenic mouse and individual-derived induced pluripotent stem cell models.,Am. J. Hum. Genet. 93 (2): 306-312. (SCI) [IF=11.025; Genetics & Heredity, 5/183= Top 2.7%; Q1]. (SCI)
H. C. Liu, S. Y. Pai, W. T. K. Cheng, H. L. Chen, T. C. Tsai, S. H. Yang, and C. M. Chen* 2013/01 Ingestion of transgenic animal milks containing the Dp2 peptide, a dust mite allergen, potentially protects mice from allergic airway inflammation and hyper-responsiveness,Allergy Asthma Clin. Immunol. 9(1): e21. (SCI) [IF=3.406; Allergy, 21/37 = Top 56.8%; Q3] [OtoRhinoLaryngology特別報導; 07/23/2013]. (SCI)
P. H. Cheng, C. L. Li, L. S. Her, Y. F. Chang, A. W. S. Chan,C.M. Chen, and S. H. Yang. 2013/01 Significantly differential diffusion of neuropathological aggregates in the brain of transgenic mice carrying N-terminal mutant huntingtin fused with green fluorescent protein,Brain Struct. Funct. 218(1): 283-94. (SCI) [IF=3.270; Anatomy & Morphology, 1/23= Top 4.3%; Q1] [SciBite News特別報導; 04/03/2012]. (SCI)
S. W. Tsai, H. L. Chen, Y. C. Chang, and C. M. Chen* 2013 Molecular Mechanisms of treadmill therapy on neuromusclar atrophy induced via botulinum toxin A,Neural Plasticity. 2013: e593271. (SCI) [IF=3.599, Neurosciences, 138/273= 50.5%; Q3]. (SCI)
H. Y. Chen, C. J. Chen, Y. N. Lin, Y. H. Chen, W. C. Chen, and C. M. Chen 2013 Proteomic analysis related to stress urinary incontinence following vaginal trauma in female mice,Eur. J. Obstet. Gynecol. Reprod. Biol. 171 (2013): 171-179. (SCI) [IF=2.435, Obstetrics & Gynecology, 60/121= 49.6%; Q2]. (SCI)
Y. T. Wang, S. Y. Chang, Y. C. Huang, T. C. Tsai, C. M. Chen, and C. T. Lim 2013 Nanomechanics insights into the performance of healthy and osteoporotic bones,Nano Lett. 13 (11): 5247-5254. [IF=13.025; Nanoscience & Nanotechnology, 4/69= Top 5.8%] [Nanowerk News特別報導; 10/10/2013]. (SCI)
Y. C. Lin, M. C. Lu, C. Lin, M. K. Chiang, M. S. Jan, H. L. Tang, H. C. Liu, W. L. Lin, C. Y. Huang, C.M. Chen* and Y. C. Lai 2013 Activation of IFN-r/STAT/IRF-1 in hepatic responses to Klebsiella pneumoniae infection,PLoS ONE 8 (11): e79961. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
W. C. Chen, K. D. Tsai, C. H. Chen, M. S. Lin, C. M. Chen, C. M. Shih, and W. Chen* 2012/09 Role of Gallium-67 scintigraphy in the evaluation of occult sepsis in the medical ICU,Intern. Emerg. Med. 7: 53-58. (SCI) [IF=3.397; Medicine, General & Internal, 55/313=17.6%; Q1]. (SCI)
J. Y. Chen, H. L. Chen, J. C. Cheng, H. J. Lin, Y. T. Tung, C. F. Lin, and C.M. Chen* 2012/06 A Chinese herbal medicine, Gexia-Zhuyu Tang (GZT), prevents dimethylnitrosamine-induced liver fibrosis through inhibition of hepatic stellate cells proliferation,J. Ethnopharmacol. 142: 811-818. [IF=4.360, Integrative & Complementary Medicine, 4/39= 10.3%; Q1]. (SCI)
J. C. Lai, M. Y. Tu*, C. M. Chen, and F. Y. Wang 2012/03 Spinal epidural abscess in the lumbar spine after dental extraction in a 53-year-old man,Formos. J. Musculoskel. Disor. 3: 144-147. (SCI).
C. J. Shen, W. T. K. Cheng, S. C. Wu, H. L. Chen, T. C. Tsai, S. H. Yang, and C.M. Chen* 2012/02 Differential differences in methylation status of putative imprinted genes among cloned swine genomes, PLoS ONE 7(2): e32812. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
S.W. Tsai, C.J. Chen, H.L. Chen, C. M. Chen* and Y. Y. Chang 2012/02 The effects of treadmill running on rat gastrocnemius function following botulinum toxin A injection,J. Orthop Res. 30 (2): 319-324. (SCI) [IF=3.494; Orthopedics, 9/63= Top 12%; Q1]. (SCI)
M. C. Chen, C. Y. Huang, S. L. Hsu, E. Lin, C. T. Ku, H. Lin*, and C. M. Chen* 2012 Retinoic acid induces apoptosis of prostate cancer DU145 cells through Cdk5 over-activation,Evid. Complement. Alter. Med. [IF=2.629, Integrative & complementary medicine, 12/29=41.4%; Q2]. (SCI)
S. W. Tsai, H. L. Chen, and C.M. Chen* 2012 The effects of treadmill on muscle activity and neuromuscular junction of botulinum toxin-induced muscle atrophy,Nova Science Publishers, Inc. New York, USA. pp.1-8.. pp.1-8.
J. Y. Chen, H. L. Chen, S. H. Wu, T. C. Tsai, M. F. Lin, C. C. Yen, W. H. Hsu, W. Chen, and C. M. Chen* 2012 Application of high-frequency ultrasound for the detection of surgical anatomy in the rodent abdomen,Vet. J. 191: 246-252. (SCI). [IF=2.688; Veterinary Sciences, 26/166= Top 15.7%; Q1]. pp. 246-252. (SCI)
78. Y. J. Chen, Y. T. Chang, J. L. Shen, T. T. Chen, C. B. Wang, C. M. Chen, and C. Y. Wu* 2012 Association between systemic antipsoriatic drugs and cardiovascular risk in patients with psoriasis with or without psoriatic arthritis: a nationwide cohort study,Arthritis & Rheumatism 64(6): 1879-1887. (SCI) [IF=7.379, Rheumatology 1/22= Top 4.5%; Q1] DOI 10.1002/art.34335. (SCI)
C. C. Yen, H. L. Chen, and C.M. Chen* 2011 Lactoferrin – a novel natural host defense protect against Escherichia coli infection. In: M. C. Rogers and N. D. Peterson, E. coli infections: Causes, Treatment and Protection,Nova Science Publishers, Inc. New York, USA. pp.113-124..
K. T. Ho, Y. H. Chang, S. H. Lu, C. N. Huang, C. M. Chen, and M. Y. Shiau* 2011 Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4,Int. J. Obesty [IF=5.095; Nutrition & Dietetics, 15/103= Top 14.6%; Q1] (SCI) (Accepted).. (SCI)
M. C. Chen, C. M. Chen*, and H. Lin* 2011 Cyclin-dependent kinase 5 regulates androgen production in mouse ovary thecal cells, Biol. Reprod. 85: 708. (SCI) [IF=4.285; Reproductive Biology, 5/30= Top 16.7%; Q1]. (SCI)
C. M. Hung, C. C. Yeh, K. Y. Chong, H. L. Chen, S. T. Kao, C. C. Yen, M. H. Yeh, M. S. Lin, and C. M. Chen* 2011 Gingyo-San enhances peripheral lymphocyte proliferation and assists infectious Bursal disease vaccination in native chicken,Evid. Complement. Alter. Med. 2011: e238208. (SCI) [IF=2.629, Integrative & complementary medicine, 12/29=41.4%; Q2]. (SCI)
T. C. Tsai, S. H. Wu, H. L. Chen, Y. T. Tung, W. T. K. Cheng, J. C. Huang and C. M. Chen* 2011 Identification of sex-specific polymorphic sequences in goat amelogenin gene for embryo sexing,J. Animal Sci. 89 (8): 2407-2414. (SCI) [IF=3.159; Agriculture, Dairy & Animal Science,9/79= Top 11.4%; Q1]. (SCI)
Y. T. Chang?,C. M. Chen?, M. Y. Tu, H. L. Chen, S. Y. Chang, T. C. Tsai, Y. T. Wang, and H. L. Hsiao 2011 Effects of osteoporosis and nutrition supplements on structures and nanomechanical properties of bone tissue,J. Mechan. Behav. Biomed. Materi. 4: 1412-1420. (SCI) [IF=3.902; Materials Science Biometerials, 17/46= 37%; Q2].†Co-first author. (SCI)
Y. C. Lin, M. C. Lu, H. L. Tang, H. C. Liu, C. H. Chen, K. S. Liu, C. Lin, C. S. Chiou, M. K. Chiang, C. M. Chen* and Y. C. Lai*. 2011 Assessment of hypermucoviscosity as a virulence factor for experimental Klebsiella pneumoniae infections: comparative virulence analysis with hypermuco- viscosity-negative strain,BMC Microbiology 11:50. [IF= 3.605; Microbiology, 50/142= 35.2%; Q2] (SCI) (獲選為2011年BMC Open Assess 190種期刊中之Highly Assessed Paper). (SCI)
Y. T. Tung, H. L. Chen, C. W. Lai, C. J. Shen, Y. W. Lai, and C. M. Chen* 2011 Curcumin reduces pulmonary tumorigenesis in vascular endothelial growth factor (VEGF)-overexpressing transgenic mice,Mol. Nutri. Food Res. 55(7): 1036-1043. (SCI) [IF=5.914; Food Science & Technology,9/160= Top 5.6%; Q1]. pp.1036-1043. (SCI)
H. C. Liu, M. S. Jan, Y. C. Lin, T. C. Wu, C. N. Huang, C. M. Chen*, and M. C. Lu* 2011 A rare pulmonary zygomycosis manifested as chronic mediastinitis and bronchial perforation,Eur. Respir. J. 38: 734-735. (SCI) [IF=16.671; Respiratory System, 3/96= 3.1%; Q1]. (SCI)
H. J. Lin, J. Y. Chen, C. F. Lin, S. T. Kao, J. C. Cheng, H. L. Chen, and C.M. Chen* 2011 Hepatoprotective effects of Yi Guan Jian, an herbal medicine, in rats with dimethylnitrosamine- induced liver fibrosis,J. Ethnopharmacol. 134: 953-960. (SCI) [IF=4.360, Integrative & Complementary Medicine, 5/29= 17.2%; Q1]. (SCI)
C. C. Yen, C. J. Shen, W. H. Hsu, Y. H. Chang, H. T. Lin, H. L. Chen and C. M. Chen*. 2011 Lactoferrin: an iron-binding antimicrobial protein against Escherichia coli infection,BioMetals 24: 585-594. (SCI) [IF=2.949; Biochemistry & Molecular Biology 201/298= 67.5%; Q3]. (SCI)
C.C. Yen, Y.W. Lai, H.L. Chen, C.W. Lai, C.Y. Lin, W. Chen, Y.P. Kuan, W.H. Hsu, and C.M. Chen*. 2011 Aerosolized human extracellular superoxide dismutase prevents hyperoxia-induced lung injury,PLoS ONE 6(10): e26870. (SCI) [IF=3.240; Multidisciplinary Sciences, 29/126 = Top 23%; Q1]. (SCI)
H.J. Lin, C.P. Tseng, C.F. Lin, M.H. Liao, C. M. Chen, S.T. Kao and J.C. Cheng* 2011 A Chinese herbal decoction, modified Yi Guan Jian, induces apoptosis in hepatic stellate cells through a ROS-mediated mitochondrial/ caspase pathway, Alter. Med. 2011: e459531. (SCI) [IF=2.629, Integrative & complementary medicine, 12/29=41.4%; Q2]. (SCI)
C. M. Hung, C. C. Yeh, H. L. Chen, C.W. Lai, M.F. Kuo, M. H. Yeh, W. Lin, M.Y. Tu, H. C. Cheng, and C. M. Chen* 2010 Porcine lactoferrin administration enhances peripheral lymphocyte proliferation and assists infectious bursal disease vaccination in native chickens,Vaccine. 28: 2895-2902. (SCI) [IF= 3.641; Medicine, Research & Experimental, 72/186= 38.7%; Q2]. (SCI)
C. H. Lin, C. J. Chen, C. M. Chen, S. L. Liao, S. L. Raung, and S. W. Tsai 2010 Treatment of atlantoaxial rotatory fixation with botulinum toxin muscle block and manipulation,J. Chin. Med. Assoc. 73: 222-224. (SCI) [IF=2.743; Medicine, General & Internal, 76/313= 24.3%; Q1]. pp.222-224. (SCI)
C. M. Hung, S. C. Wu, C. C. Yen, M. F. Lin, Y. W. Lai, Y. T. Tung, H. L. Chen, and C. M. Chen*. 2010 Porcine lactoferrin as feedstuff additive elevates avian immunity and potentiates vaccination,BioMetals. 23: 579-587. (SCI) [IF=2.949; Biochemistry & Molecular Biology 201/298= 67.4%; Q3]. (SCI)
M.S. Lee, C.H. Lin, T.H. Lee, H.M. Wu, C.C. Huang, L.S. Huang, C. M. Chen and E.H. Cheng* 2010 Association of creatin kinase B and peroxiredoxin 2 expression with age and embryo quality in cumulus cells, J. Assist. Reprod. Genet. 27: 629-639. (SCI) [IF=3.412; Obstetrics & Gynecology, 25/83= 30.1%; Q2]. pp.629-639. (SCI)
K. T. Ho§, M. Y. Shiau, Y. H. Chang, C. M. Chen§, S. C. Yang, and C. N. Huang* 2010 Association of interleukin-4 promoter polymorphisms in Taiwanese patients with type 2 diabetes mellitus, Metabol. Clin. Exp. 59: 1717-1722. (SCI) [IF=8.694, Endocrinology & Metabolism, 11/177=6.2%; Q1] (§Equal contribution).. (SCI)
T. C. Tsai, W. Lin, S. H. Yang, W.T.K. Cheng, E.H. Cheng, M.S. Lee, K.Y. Chang, and C. M. Chen* 2010 Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition,BMC Dev. Biol. 10: 88. [IF=1.978, Developmental Biology, 19/40=47.5%; Q2] (獲選為2010年BMC Open Assess 190種期刊中之Highly Assessed Paper). (SCI)
F. C. Liu, H. L. Chen, W. Lin, Y.T. Tang, C.W. Lai, A. L. Hsu, and C. M. Chen* 2010 Application of porcine lipase secreted by Pichia pastoris to improve fat digestion and growth performance of postweaning piglets, J. Agri. Food Chem. 58: 3322-3329. (SCI). [IF=5.279; Agriculture, Multidisciplinary 6/83 = Top 7.2 %; Q1]. (SCI)
H. L. Chen, Y.W. Lai, C. S. Chen, T. W. Chu, W. Lin, C. C. Yen, M. F. Lin, M.Y. Tu, and C. M. Chen*. 2010 Probiotic Lactobacillus casei expressing human lactoferrin elevates antibacterial activity in the gastrointestinal tract,BioMetals. 23: 543-554. (SCI) [IF=2.949; Biochemistry & Molecular Biology 201/298= 67.5%; Q3]. (SCI)
Y. J. Chen, J. L. Shen, C. Y. Wu, S. Y. Chu, Y. T. Chang, C. M. Chen and F. Y. Lee 2009 Elevated plasma osteopontin level is 1 associated with occurrence of psoriasis and is an unfavorable cardiovascular risk factor in patients with psoriasis,J. Am. Acad. Dermatol. 60(2): 225-230. (SCI) [IF=11.527, Dermatology 1/89= Top 1.1%; Q1]. (SCI)
C. C. Yen, C. Y. Lin, K. Y. Chong, T. C. Tsai, C. J. Shen, M. F. Lin, C. Y. Su, H. L. Chen and C. M. Chen* 2009 Lactoferrin as a natural regimen of selective decontamination of the digestive tract,J. Infect. Dis. 199(4): 590-598. (SCI) [IF=5.226, Infectious diseases, 18/92=Top19.6%; Q1] [NaturalNews.com特別報導]. (SCI)
Y. J. Chen, C. Y. Wu, C. C. Chang, C. J. Ma, M. C. Li, and C. M. Chen* 2008 Nuclear Kruppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis,Cancer Biol. Ther. 7(5): 777-782. (SCI) [IF=4.742, Oncology 102/308= 33.1%; Q2]. no.5, pp.777-782. (SCI)
H. L. Chen, L. C. Wang, C. H. Chang, C. C. Yen, W.T.K. Cheng, S. C. Wu, C. M. Hung, M. F. Kuo, and C. M. Chen* 2008 Recombinant Porcine Lactoferrin Expressed in the Milk of Transgenic Mice Protects Neonatal Mice from a Lethal Challenge with Enterovirus Type 71,Vaccine. 26: 891-898 (SCI) [IF=3.641; Medicine, Research & Experimental, 72/186= 38.7%; Q2]. (SCI)
H. L. Chen, J. Y. Huang, T. W. Chu, T. C. Tsai, C. M. Hung, C. C. Lin, L. C. Wang, Y. J. Chen, M. F. Lin, and C. M. Chen* 2008 Expression of VP1 protein in the milk of transgenic mice: As a potential oral vaccine against for enterovirus 71 strain infection, Vaccine. 26: 2882-2889. (SCI) [IF= 3.641; Medicine, Research & Experimental, 72/186= 38.7%; Q2]. (SCI)
F. C. Liu, H. L. Chen, K. Y. Chong, A. L. Hsu, and C. M. Chen* 2008 Production of recombinant porcine colipase secreted by Pichia pastoris and its application to improve dietary fat digestion and growth of postweaning piglets,Biotech. Prog. 24: 1333-1341. (SCI) [IF=2.681, Food Science & Technology,71/160= 44.4%; Q2].. pp.1333-1341. (SCI)
Y. J. Chen, C. Y. Wu, J. L. Shen, S. Y. Chu, C. K. Chen, Y. T. Chang.and C. M. Chen* 2008 Psoriasis independently associated with hyperleptinemia contributing to metabolic syndrome,Arch Dermatol. 144(12): 1571-1575. (SCI) [IF=4.789, Dermatology; 2/63= Top 3.2%; Q1]. [Leading News特別報導]. (SCI)
C. F. Tu, H. C. Tsai, C. M. Chen, J. M. Lee, T. S. Yang, Y. L. Tseng, N. K. Chou, and P. H. Lee 2008 Human leukocyte antigen-DR matching improved skin graft survival from transgenic pigs to accommodate SCID mice reconstituted with human peripheral blood mononuclear cells,Transplant. Proc. 40(2): 578-580. (SCI) [IF=1.066, Transplantation 24/25= 96%; Q4]. (SCI)
C. M. Chen*, W. E. Chen, C. Y. Chen, J. C. Wu, and H. L. Chen 2007 Dissecting epigenetic alterations between hepatitis B virus and hepatitis C virus-infected hepatocellular carcinoma using CpG island microarray, J. Hepatol. 46: 127. (SCI). [IF= 25.083; Gastroenterology & Hepatology 2/92 = Top 2.2 %; Q1]. (SCI)
F. C. Liu, and C. M. Chen* 2007 Cloning myostatin propeptide cDNA and construction of its expression vector,Taiwan Livestock Res. 40: 159-168..
F. C. Liu, and C. M. Chen* 2007 Cloning of myostatin cDNA and analysis of the relation between birth weight and myostatin mRNA expression levels of neonatal TLRI No.1 black pigs,Taiwan Livestock Res. 40: 119-128..
K. M. Lin, T. H. Chao, C. M. Chen, L. P. Chen, H. M. Wang, and F. F. Chiang 2007 Methylation of the PCDH21 (Protocadherin-21) gene in colorectal cancer, J. Soc. Colon Rectal Surg. 18: 93-98. (SCI).. pp.93-98. (SCI)
S. C. Wu, H. L. Chen, C. C. Yen, M. F. Kuo, T. S. Yang, S. R. Wang, C. N. Weng, C. M. Chen*, and W. T. K. Cheng 2007 Recombinant porcine lactoferrin expressed in the milk of transgenic mice enhances offspring growth performance, J. Agri. Food Chem. 55: 4670-4677. (SCI). [IF=5.279; Agriculture, Multidisciplinary 5/58 = Top 8.6 %; Q1] ( 榮獲ACS美國化學學會News特別報導；並被撰文收錄於J. Chem. Edu.期刊作為美國高中及大學生物與化學之參考教材). (SCI)
F. C. Liu, and C. M. Chen* 2007 The effect of dietary addition of the recombinant colipase on growth performance and fat utilization of TLRI black piglets 2wks postweaning,Taiwan Livestock Res. 40: 169-175.. pp.169-175.
H. L. Chen, C. C. Yen, C. Y. Lu, C. H. Yu, and C. M. Chen* 2006 Synthetic Porcine Lactoferricin with a 20-Residue Peptide Exhibits Antimicrobial Activity against Escherichia coli, Staphylococcus aureus, and Candida albicans, J. Agri. Food Chem. 54: 3277-3282. (SCI). [IF=5.279; Agriculture, Multidisciplinary 5/58 = Top 8.6 %; Q1]. (SCI)
H.L. Chen, C.C. Yen, T.C. Tsai, C.H. Yu, Y.J. Liou, Y.W. Lai, M.L. Wang, and C.M. Chen* 2006 Production and characterization of human extracellular superoxide dismutase in the methylotrophic yeast, Pichia pastoris,J. Agri. Food Chem. 54: 8041-8047. (SCI). [IF=5.279; Agriculture, Multidisciplinary 5/58 = Top 8.6 %; Q1] [ACS News]. (SCI)
C. J. Hu, S. D. Chen, D. I. Yang, T. N. Lin, C. M. Chen, T. H. M. Huang and C. Y. Hsu 2006 Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells,J. Cereb. Blood Flow Metabol. 26: 1519-1526. (SCI) [IF=6.200; Hematology10/93= Top 10.8%; Q1]. (SCI)
C. C. Yen, S. H. Yang, C. Y. Lin, and C. M. Chen* 2006 Stem cells in the lung parenchyma and prospects for lung injury therapy,Eur. J. Clin. Invest. 36: 310-319. (SCI). [IF=4.686; Medicine, General & Internal, 48/313= 15.3 %; Q1]. pp.310-319. (SCI)
H. L. Chen, Y. W. Lai, C. C. Yen, Y. Y. Lin, C.Y. Lu, S. H. Yang, T. C. Tsai, C. W. Lin and C. M. Chen* 2005 Production of recombinant porcine lactoferrin exhibiting antibacterial activity in methylotrophic yeast, Pichia pastoris,J. Mol. Microbiol. Biotechnol. 8: 141-149. (SCI) [IF=0.803; Biotechnology & Applied Microbiology 152/156 = 97.4%; Q4]. pp.141-149. (SCI)
S. H. Wei, T. C. Yip, and C. M. Chen*. 2005 Identifying clinicopathological association of DNA hypermethylation in cancers using CpG island microarrays. In: DNA Methylation and Cancer Therapy,Kluwer Academic. NY, USA. p.107-116. pp.107-116.
S. Y. Pai, S. H. Yang, W. T. K. Cheng, C. H. Hsu and C.M. Chen*. 2004 Desensitivity therapy of allergic airway inflammation and hyper-reactivity by mammary specific expre.
S. H. Tsai, C. M. Chen, C. S. Chang, and G. H. Chen 2004 Effect of Helicobacter pylori infection on intragastric acidity in patients with reflux esophagitis,J. Gastroenterol. 39: 821-826. (SCI) [IF=7.527; Gastroenterology & Hepatology, 17/92= Top 18.5%; Q1]. pp.821-826. (SCI)
C. M. Chen, H. L. Chen, T. H. C. Hsiau, A. H. A. Hsiau, H. Shi, G. J. R. Brock, S. H. Wei, C. W. Caldwell, P. S. Yan, and T. H. M. Huang 2003 Methylation target array for rapid analysis of CpG island hypermethylation in multiple tissue genomes,Am. J. Pathol. 163: 37-45. (SCI) [IF= 4.307; Pathology, 12/89= Top 13.5%; Q1]. (SCI)
H. Yang, C. M. Chen, P. S. Yan, T. H. M. Huang, H. Shi, M. Burger, I. Nimmrich, S. Maier, K. Berlin, and C. W. Caldwell 2003 The androgen receptor gene is preferentially hypermethylated in follicular non-Hodgkin’s lymphomas,Clin. Cancer Res. 9: 4034-4042. (SCI) [IF= 12.531; oncology, 12/308= Top 3.4%; Q1]. (SCI)
S. H. Wei, C. M. Chen, G. Strathdee, J. Harnsomburana, C. R. Shyu, F. Rahmatpanah, H. Shi, S. W. Ng, P. S. Yan, K. P. Nephew, R. Brown, and T. H. M. Huang 2002 Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers,Clin. Cancer Res. 8: 2246-2252. (SCI) [IF= 12.531; oncology, 12/308= Top3.4%; Q1]. (SCI)
C. M. Chen*, C. H. Wang, S. C. Wu, C. C. Lin, S. H. Lin, and W. T. K. Cheng 2002 Temporal and spatial expression of biologically active human factor VIII in the milk of transgenic mice driven by mammary-specific bovine -lactalbumin regulation sequences,Transgenic Res. 11: 257-268. (SCI) [IF=2.788; Biochemical Research Methods, 46/77=59.7%;Q3]. (SCI)
J. C. Wu, C. M. Chen, T. Y. Chiang, W. H. Tsai, W. J. Jeng, I. J. Sheen, C. C. Lin, and X. J. Meng 2002 Spread of hepatitis E virus among different-aged pigs: Two-year survey in Taiwan,J. Med. Virol. 66: 488- 492. (SCI) [IF=2.327; Virology , 28/36=77.8%,Q3]. (SCI)
H. Shi, P. S. Yan, C. M. Chen, F. Rahmatpanah, C. Lofton-Day, C. W. Caldwell, and T. H. M. Huang 2002 Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells,Cancer Res. 62: 3214-3220. (SCI) [IF=12.701; oncology, 20/308=Top6.5%; Q1]. (SCI)
C. M. Chen, H. L. Chen, H. Shi, C. W. Caldwell, G. J. R. Brock, P. S. Yan, and T. H. M. Huang 2002 Complex patterns of DNA methylation in cancer,In: Cancer Epigenetics: DNA methylation and chromatin. Madrid, Spanish.. pp.43-44.
P. S. Yan, C. M. Chen, H. Shi, F. Rahmatpanah, S. H. Wei, and T. H. M. Huang 2002 Applications of CpG island microarrays for high-throughput analysis of DNA methylation,J. Nutri. 132: 2430- 2434. (SCI) [IF=4.798; Nutrition & Dietetics, 17/103= Top16.5%; Q1]. (SCI)
S. C. Liu, C. M. Chen, and Y. H. Yu 2002 Sex identification of duck embryos by polymerase chain reaction,Taiwan Livestock Res. 35: 169-173. pp.169-173.
R. S. Gitan, H. Shi, C. M. Chen, P. S Yan, and T. H. M. Huang 2002 Methylation-specific oligonucleotide microarray: A new potential for high-throughput methylation analysis,Genome Res. 12: 158-164. (SCI) [IF=9.043; Genetics & Heredity , 7/183= Top3.8%; Q1]. pp.158-164. (SCI)
G. J. R. Brock, T. H. M. Huang, C. M. Chen, and K. J. Johnson 2001 A novel technique for the identification of CpG islands exhibiting altered methylation patterns (ICEAMP) ,Nucl. Acids Res. 29(24): e123. (SCI) [IF=16.971; Biochemistry & Molecular Biology, 4/300=Top1.3%; Q1]. (SCI)
P. S. Yan, C. M. Chen, H. Shi, F. Rahmatpanah, S. H. Wei, C. W. Caldwell, and T. H. M. Huang 2001 Disecting complex epigenetic alterations in breast cancer using CpG island microarrays,Cancer Res. 61: 8375-8380. (SCI) [IF=12.701; oncology, 20/308=Top6.5%; Q1]. (SCI)
C. M. Chen*, Y. C. Chang, H. L. Chen, and W. T. K. Cheng 2000/08 High-level expression of growth hormone in the methylotropic yeast and its application on growth improvement of fowls ,Asian-Aus. J. Anim. Sci. 13: 158-161. (SCI) [IF=2.509; Biochemistry & Molecular Biology, 17/79=21.5%; Q1]. (SCI)
W. T. K. Cheng, C. H. Lee, C. M. Hung, T. J. Chang and C. M. Chen* 2000/05 Growth hormone gene polymorphisms and growth performance traits in Duroc, Landrace and Tao-Yuan pigs,Theriogenology 54:1225-1237. (SCI) [IF=2.740; Reproductive Biology, 5/33=Top15.1%; Q1]. pp.1225-1237. (SCI)
C. M. Hung, T. H. Hong, C. H. Hsu, and C. M. Chen* 2000 Production of anti-insulin monoclonal antibody by a novel immunization protocol and its clinical application to ELISA of insulin,J. Agri. Soci. China 1: 343-352. pp.343-352.
C. M. Chen, Winston T. K. Cheng, Y. C. Chang, T. J. Chang, and C. L. Chen 2000 Growth enhancement of fowls by dietary administration of recombinant yeast cultures containing enriched growth hormone,Life Sci.67: 2103-2115. (SCI) [IF=5.037; Medicine, Research & Experimental, 35/186=18.8%; Q1]. pp.2103-2115. (SCI)
J. C. Wu, C. M. Chen, W. H. Tsai, T. Z. Chen, and S. D. Lee 2000 Clinical and epidemiological implications of swine hepatitis E virus infection,J. Med. Virol.60: 166-171. (SCI) [IF=2.327; Virology, 24/36= 66.7%;Q3]. pp.166-171. (SCI)
C. M. Chen, C. L. Hu, and W. T. K. Cheng 1999 The techniques of bovine embryo sexing,Natl. Sci. Coun. Monthly (ROC) . vol.27, pp.381-392.
M. F. Kuo, C. M. Chen, H. K. Hu, and W. T. K. Cheng. 1999 The feasibleness of using mouse embryonic stem cells after retrovirus vector-PSN transfection to aggregate with mouse diploid and tetraploid embryos for production of transgenic mice,. Chin. Soc. Anim. Sci.28: 471-490.. pp.471-490.
C. M. Chen, C. L. Hu, C. H. Wang, C. M. Hung, H. K. Wu, K. B. Choo, and W. T. K. Cheng 1999 Gender determination in single bovine blastomeres by polymerase chain reaction amplification of sex-specific polymorphic fragments in the amelogenin gene, Mol. Reprod. Dev. 54: 209-214. (SCI) [IF=2.609; Reproductive Biology, 21/30=70%;Q3]. pp.209-214. (SCI)
M. F. Kuo, C. M. Chen, H. K. Hu, and W. T. K. Cheng 1998 Integration and expression of porcine growth hormone gene after transfected into the mouse embryonic stem cells by retroviral vector,J. Chin. Soc. Anim. Sci. 27(1): 59-73.. pp.59-73. (SCI)
M. F. Kuo, C. M. Chen, H. K. Hu, and W. T. K. Cheng. 1998 Use of nonautologous microencapulated fibroblasts in growth hormone gene therapy to improve growth of midget swine,Hum. Gene Ther. 9: 1995-2003. (SCI) [IF=5.695; Biotechnology & Applied Microbiology, 19/161= Top 11%; Q1]. pp.59-73. (SCI)
K. B. Choo, C. M. Chen, and W. T. K. Cheng. 1996 1996 Molecular analysis of cellular loci disrupted by papillomavirus 16 integration in cervical cancer: frequent viral integration in topologically destabilized and transcriptionally active chromosomal regions,J. Med. Virol. 49: 15-22. (SCI) [IF=2.327; Virology, 28/36=77.8%;Q4] . pp.15-22. (SCI)
J. C. Wu, C. M. Chen, T. Z. Chen, S. D. Lee, F. S. Yen, and K. B. Choo, 1996 Prevalence and type of precore hepatitis B virus mutants in hepatitis D virus superinfection and its clinical implications,J. Infect. Dis. 173: 457-459. (SCI) [IF=5.226, Infectious diseases, 18/92= Top19.6%; Q1]. (SCI)
J. C. Wu, C. M. Chen, I. J. Sheen, S. D. Lee, H. M. Tzeng, and K. B. Choo 1996 Evidence of transmission of hepatitis D virus to spouses from sequence analysis of the viral genome,Hepatology 22: 1656-1660. (SCI) [IF=17.425; Gastroenterology & Hepatology, 6/131= Top 4.6%; Q1]. (SCI)
K. B. Choo, C. J. Huang, C. M. Chen, C. P. Han, and L. C. Au 1995 Jun-B oncogene aberrations in cervical cancer cell lines,Cancer Letters 93: 249-253. (SCI) [IF=8.679; Oncology, 27/308 =Top8.8%; Q1] . pp.249-253. (SCI)
C. M. Chen, W. T. K. Cheng, and K. B. Choo, 1995 Frequent deletions and sequence aberrations at the transgene junctions of transgenic mice carrying the papillomavirus regulatory and the SV40 TAg gene sequences, Transgenic Res. 4: 52-59. (SCI) [IF=2.788; Biochemistry & Molecular Biology, 211/298=70.8%;Q3]. pp.52-59. (SCI)
J. C. Wu, K. B. Choo, C. M. Chen, T. Z. Chen, and S. D. Lee 1995 Genotyping of hepatitis D virus by restriction-fragment length polymorphism and relation to outcome of hepatitis D,Lancet 346: 939-941. (SCI) [IF=79.321; Medicine, General & Internal, 2/169 = 1.2%; Q1]. (SCI)
K. B. Choo, C. M. Chen, C. N. Shen, and L. C. Au, 1995 Resolution of uncertainties in restriction maps of cosmid clones by ,Anal. Biochem. 288: 355-357. (SCI) [IF=3.365; Biochemistry & Molecular Biology, 135/300=45.0%;Q2]. pp.355-357. (SCI)
C. M. Chen*, W. T. K. Cheng, and K. B. Choo 1994/06 Structure analysis of transgenes in transgenic mice: evidence for frequent deletions, insertions and sequence aberrations. ,Asian-Aus. J. Anim. Sci. 7: 15-18. (SCI) [IF=2.509; Agriculture, Dairy & Animal Science, 14/63=22.2%; Q1]. pp.15-18. (SCI)
K. B. Choo, and C. M. Chen, 1994 Cellular genes and sequences disrupted by human papillomavirus integration in cervical cancer,J. Cell. Biochem. 18A: 224-225. (SCI) [IF=4.429; Biochemistry & Molecular Biology, 112/298=37.9%;Q2] . pp.224-225. (SCI)
C. M. Chen, M. P. Shyu, L. C. Au, H. W. Chu, W. T. K. Cheng, and K. B. Choo 1994 Analysis of deletion of the integrated HPV16 sequences in cervical cancer: a rapid multiplex PCR approach, J. Med. Virol. 44: 206-211. (SCI) [IF=2.327; Virology, 28/36=77.8%;Q4]. pp.206-211. (SCI)
K. Y. Chong, C. M. Chen, and K. B. Choo 1993 Post-hybridization recovery of DNA from membrane filter for polymerase chain reaction (PCR) amplification. ,BioTechniques 14: 575-578. (SCI) [IF=1.993; Biochemistry & Molecular Biology, 253/298=84.9%;Q4]. pp.575-578. (SCI)
