Laposchan S, Yang YF, Chan KH, Gonzalez RM, Gabriel W, Wilhelm M, Hung HC*, Lee CY (2026) Decoding isozyme-specific substrate recognition in protein arginine deiminases by in vitro proteome-wide citrullination mapping. Nature Commun. (Accepted) (Corresponding author)
Chen TY, Lin YC, Liu GY, Hung HC* (2026) Comparative effectiveness of telmisartan vs. other angiotensin receptor blockers in reducing hypertension-related cerebrovascular and cardiovascular events: a real-world retrospective study using the TriNetX network. Front. Cardiovasc. Med. 2026 Jan 22;12:1715032. doi: 10.3389/fcvm.2025.1715032. (Corresponding author)
Chen TY, Deng YL, Chen IC, Lin CH, Lin JF, Chen YM, Lee HT, Hung HC* (2026) Medication-related osteonecrosis of the jaw following osteoporosis therapy: A real-world retrospective cohort study using the TriNetX global collaborative network. Bone 2026 Jan;202:117678. doi: 10.1016/j.bone.2025.117678. (Corresponding author)
Yang YF, Lee CY, Liu GY, Hsieh JY, Lin YC, Wang LW, Chan KH, Yen WS, Chen YC, Lin CL, Hung HC* (2025) Citrullination negatively regulates the functions of the p53 protein and opposes its ubiquitination and degradation. Proc. Natl. Acad. Sci. U. S. A. 122(42):e2423526122. doi: 10.1073/pnas.2423526122. (Corresponding author)
Liao LC, Fu YC, Lee PC, Jan SL, Lin MC, Chuang CM, Hung HC* (2025) Short-term outcomes of transcatheter perimembranous ventricular septal defect closure using the konar-multifunctional occluder: the Taiwanese experience. Front. Cardiovasc. Med. 2025 May 27;12: 1572812. doi: 10.3389/fcvm.2025.1572812. (Corresponding author)
Tsou SH, Luo KS, Huang CN, Kornelius E, Cheng IT, Hung HC, Hung YC, Lin CL, Hsu MY (2025) Liraglutide Attenuates FFA-Induced Retinal Pigment Epithelium Dysfunction via AMPK Activation and Lipid Homeostasis Regulation in ARPE-19 Cells. Int. J. Mol. Sci. 26(8):3704. doi: 10.3390/ijms26083704.
Liao LC, Chen YY, Fu YC, Hung HC* (2025) Correlation between pulmonary to systemic flow ratio and N-terminal Pro-B-type natriuretic peptide level in children with atrial septal defect. Front. Cardiovasc. Med. 2025 Mar 14;12: 1522603. doi: 10.3389/fcvm.2025.1522603 (Corresponding author)
Hsieh JY, Leong PY, Yang YF, Liu YL, Liu GY, Hung HC* (2024) Protein degradation of antizyme depends on the N-terminal degrons. Protein Sci. 33(11):e5199. doi: 10.1002/pro.5199. (Corresponding author)
Lin SC, Chang CC, Tsou SH, Chiu PY, Cheng JF, Hung HC, Chen WJ, Ho YJ, Lin CL (2024) Protective Effects of Ambroxol on Aβ and α-Synuclein-Induced Neurotoxicity Through Glucocerebrosidase Activation in HT-22 Hippocampal Neuronal Cells. Int. J. Mol. Sci. 25(22):12114. doi: 10.3390/ijms252212114.
Tsou SH, Lin SC, Chen WJ, Hung HC, Liao CC, Kornelius E, Huang CN, Lin CL, Yang YS (2024) Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells. Biomedicines 12(7):1444. doi: 10.3390/biomedicines12071444.
Chen KC, Hsiao IH, Huang YN, Chou YT, Lin YC, Hsieh JY, Chang YL, Wu KH, Liu GY, Hung HC* (2023) Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia. Cell Oncol (Dordr). 46(5):1301-1316. doi: 10.1007/s13402-023-00812-x. (Corresponding author)
Hsieh JY, Chen KC, Wang CH, Liu GY, Ye JA, Chou YT, Lin YC, Lyu CJ, Chang RY, Liu YL, Li YH, Lee MR, Ho MC, Hung HC* (2023) Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration. Commun. Biol. 6(1):548. doi: 10.1038/s42003-023-04930-y. (Corresponding author)
Liu YL, Hsiao IH, Lin YH, Lin CL, Jan MS, Hung HC*, Liu GY (2022) Ornithine decarboxylase functions in both autophagy and apoptosis in response to ultraviolet B radiation injury. J Cell Physiol. 237(4):2140-2154. doi: 10.1002/jcp.30678. (Corresponding author)
Yang YF, Wang CM, Hsiao IH, Liu YL, Lin WH, Lin CL, Hung HC*, Liu GY (2022) Peptidylarginine deiminase 2 promotes T helper 17-like T cell activation and activated T cell-autonomous death (ACAD) through an endoplasmic reticulum stress and autophagy coupling mechanism. Cell Mol. Biol. Lett. 27(1):19. doi: 10.1186/s11658-022-00312-0. (Corresponding author)
Chang CC, Tsou SH, Chen WJ, Ho YJ, Hung HC, Liu GY, Singh SK, Li HH, Lin CL (2021) miR-302 Attenuates Mutant Huntingtin-Induced Cytotoxicity through Restoration of Autophagy and Insulin Sensitivity. Int. J. Mol. Sci. 22 (16):8424. doi: 10.3390/ijms22168424.
Yang YF, Lee CY, Hsieh JY, Liu YL, Lin CL, Liu GY, Hung HC* (2021) Regulation of Polyamine Homeostasis through an Antizyme Citrullination Pathway. J Cell Physiol. 236(8):5646-5663. doi: 10.1002/jcp.30252. (Corresponding author)
Hsieh JY, Yang HP, Tewary SK, Cheng HC, Liu YL, Tai SC, Chen WL, Hsu CH, Huang TJ, Chou CJ, Huang YN, Peng CT, Ho MC, Liu GY, Hung HC* (2021) Single nucleotide variants lead to dysregulation of the human mitochondrial NAD(P)+-dependent malic enzyme. iScience. 24(2):102034. doi: 10.1016/j.isci.2021.102034. (Corresponding author)
Liu YC, Liu YL, Hsieh JY, Wang CH, Lin CL, Liu GY, Hung HC* (2020) Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase. Nutrients 12(12):3867. doi: 10.3390/nu12123867. (corresponding author)
Chang CC, Li HH, Tsou SH, Hung HC, Liu GY, Korolenko TA, Lai TJ, Ho YJ, Lin CL (2020) The Pluripotency Factor Nanog Protects against Neuronal Amyloid β-Induced Toxicity and Oxidative Stress through Insulin Sensitivity Restoration. Cells 9(6):1339. doi: 10.3390/cells9061339.
Hsieh JY, Liu YC, Cheng IT, Lee CJ, Wang YH, Fang YS, Liu YL, Liu GY, Hung HC* (2019) Critical Factors in Human Antizymes that Determine the Differential Binding, Inhibition, and Degradation of Human Ornithine Decarboxylase. Biomolecules 9(12). pii: E864. doi: 10.3390/biom9120864. (corresponding author)
Hsieh JY, Shih WT, Kuo YH, Liu GY, Hung HC* (2019) Functional Roles of Metabolic Intermediates in Regulating the Human Mitochondrial NAD(P)+-Dependent Malic Enzyme. Sci. Rep. 9(1):9081. doi: 10.1038/s41598-019-45282-0. (corresponding author)
Cheng YW, Chang CC, Chang TS, Li HH, Hung HC, Liu GY, Lin CL (2019) Aβ stimulates microglial activation through antizyme-dependent downregulation of ornithine decarboxylase. J Cell Physiol. 234(6):9733-9745. doi: 10.1002/jcp.27659.
Liu YL, Lee CY, Huang YN, Chen HY, Liu GY, Hung HC* (2017) Probing the Roles of Calcium-Binding Sites during the Folding of Human Peptidylarginine Deiminase 4. Sci. Rep. 7(1):2429. doi: 10.1038/s41598-017-02677-1. (corresponding author)
Lee CY, Lin CC, Liu YL, Liu GY, Liu JH, Hung HC* (2017) Molecular Interplay between the Dimer Interface and the Substrate-Binding Site of Human Peptidylarginine Deiminase 4. Sci. Rep. 7:42662. doi: 10.1038/srep42662. (corresponding author)
Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC*, Holers VM, Ho IC (2016) A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 1(17):e90045.
Wu HY, Chen SF, Hsieh JY, Chou F, Wang YH, Lin WT, Lee PY, Yu YJ, Lin LY, Lin TS, Lin CL, Liu GY, Tzeng SR, Hung HC*, Chan NL (2015) Structural basis of antizyme-mediated regulation of polyamine homeostasis. Proc. Natl. Acad. Sci. USA 112(36):11229-11234. (corresponding author)
Liu YC, Lee CY, Lin CL, Chen HY, Liu GY, Hung HC* (2015) Multifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor. Oncotarget 6(27):23917-23929. (corresponding author)
Hsieh JY, Li SY, Tsai WC, Liu JH, Lin CL, Liu GY, Hung HC* (2015) A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence. Oncotarget 6(24):20084-20098. (corresponding author)
Tung WF, Chen WJ, Hung HC*, Liu GY, Tung JN, Huang CC, Lin CL (2015) 4-Phenylbutyric Acid (4-PBA) and Lithium Cooperatively Attenuate Cell Death during Oxygen-Glucose Deprivation (OGD) and Reoxygenation. Cell Mol. Neurobiol. 35(6):849-859.
Liao YF, Tzeng YM, Hung HC*, Liu GY (2015) Dibenzoylmethane, hydroxydibenzoylmethane and hydroxymethyldibenzoylmethane inhibit phorbol-12-myristate 13-acetate‑induced breast carcinoma cell invasion. Mol. Med. Rep. 11(6):4597-4604.
Li HH, Lu FJ, Hung HC*, Liu GY, Lai TJ, Lin CL (2015) Humic Acid Increases Amyloid β-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells. Int. J. Mol. Sci. 16(5):10426-10442.
Chang YL, Gao HW, Chiang CP, Wang WM, Huang SM, Ku CF, Liu GY, Hung HC* (2015) Human Mitochondrial NAD(P)+-Dependent Malic Enzyme Participates in Cutaneous Melanoma Progression and Invasion. J. Invest. Dermatol. 135(3):807-815. (corresponding author)
Liao CL, Chen CM, Chang YZ, Liu GY, Hung HC*, Hsieh TY, Lin CL (2014) Pine (Pinus morrisonicola Hayata) Needle Extracts Sensitize GBM8901 Human Glioblastoma Cells to Temozolomide by Downregulating Autophagy and O6-Methylguanine-DNA Methyltransferase Expression. J. Agric. Food Chem. 62(43):10458-10467.
Hsieh JY, Li SY, Chen MC, Yang PC, Chen HY, Chan NL, Liu JH, Hung HC* (2014) Structural characteristics of the nonallosteric human cytosolic malic enzyme. Biochim. Biophys. Acta. 1844(10):1773-1783. (corresponding author)
Lee CY, Liu YL, Lin CL, Liu GY, Hung HC* (2014) Functional roles of the dimer-interface residues in human ornithine decarboxylase. PLoS One 9(8):e104865. (corresponding author)
Hsieh JY, Liu JH, Yang PC, Lin CL, Liu GY, Hung HC* (2014) Fumarate Analogs Act as Allosteric Inhibitors of the Human Mitochondrial NAD(P)+-Dependent Malic Enzyme. PLoS One 9(6):e98385. (corresponding author)
Hsu PC, Liao YF, Lin CL, Lin WH, Liu GY, Hung HC* (2014) Vimentin Is Involved in Peptidylarginine Deiminase 2-Induced Apoptosis of Activated Jurkat Cells. Mol. Cells 37(5): 426-434. (corresponding author)
Liu YL, Tsai IC, Chang CW, Liao YF, Liu GY, Hung HC* (2013) Functional roles of the non-catalytic calcium-binding sites in the N-terminal domain of human peptidylarginine deiminase 4. PLoS One 8(1):e51660. (corresponding author)
Murugan S, Hung HC* (2012)Biophysical characterization of the dimer and tetramer interface interactions of the human cytosolic malic enzyme. PLoS One 7(12):e50143. (corresponding author)
Liu YC, Hsu DH, Huang CL, Liu YL, Liu GY, Hung HC* (2011) Determinants of the differential antizyme-binding affinity of ornithine decarboxylase. PLoS One 6(11):e26835. (corresponding author)
Wu CL, Liao YF, Hung YC, Lu KH, Hung HC*, Liu GY (2011) Ornithine decarboxylase prevents dibenzoylmethane-induced apoptosis through repressing reactive oxygen species generation. J. Biochem. Mol. Toxicol. 25(5): 312-319.
Hsieh JY, Chen MC, Hung HC* (2011) Determinants of Nucleotide-Binding Selectivity of Malic Enzyme. PLoS One 6(9):e25312. (corresponding author)
Hsieh JY, Yang JY, Lin CL, Liu GY, Hung HC* (2011) Minimal antizyme peptide fully functioning in the binding and inhibition of ornithine decarboxylase and antizyme inhibitor. PLoS one 6(9): e24366. (corresponding author)
Liu YL, Chiang YH, Liu GY, Hung HC* (2011) Functional role of dimerization of human peptidylarginine deiminase 4 (PAD4). PLoS one 6(6): e21314. (corresponding author)
Liu YC, Liu YL, Su JY, Liu GY, Hung HC* (2011) Critical Factors Governing the Difference in Antizyme-Binding Affinities between Human Ornithine Decarboxylase and Antizyme Inhibitor. PLoS one 6(4): e19253. (corresponding author)
Wang MF, Liao YF, Hung YC, Lin CL, Hour TC, Lue KH, Hung HC*, Liu GY (2011) Hydroxydibenzoylmethane induces apoptosis through repressing ornithine decarboxylase in human promyelocytic leukemia HL-60 cells. Exp. Mol. Med. 43(4): 189-196.
Hsieh WC, Hsu PC, Liao YF, Young ST, Wang ZW, Lin CL, Tsay GJ, Lee H, Hung HC*, Liu GY (2010) Overexpression of ornithine decarboxylase suppresses thapsigargin-induced apoptosis. Mol. Cells 30(4):311-318. (corresponding author)
Chang HP, Liang WC, Lyu RC, Chi MC, Wang TF, Su KL, Hung HC*, Lin LL (2010) Effects of C‐terminal truncation on autocatalytic processing of Bacillus licheniformis gamma‐glutamyl transpeptidase. Biochemistry (Mosc) 75(7):919‐929.
Su KL, Liao YF, Hung HC*, Liu GY (2009) Critical factors determining dimerization of human antizyme inhibitor. J. Biol. Chem. 284(39):26768-26777. (corresponding author)
Su KL, Chang KY, Hung HC* (2009) Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. Bioorg. Med. Chem. 17(15):5414-5419. (corresponding author)
Hsieh JY, Chen SH, Hung HC* (2009) Functional roles of the tetramer organization of malic enzyme. J. Biol. Chem. 284(27):18096-18105. (corresponding author)
Hsieh JY, Su KL, Ho PT, Hung HC* (2009) Long-range interaction between the enzyme active site and a distant allosteric site in the human mitochondrial NAD(P)+-dependent malic enzyme. Arch. Biochem. Biophys. 487(1):19-27. (corresponding author)
Hsieh JY, Liu JH, Fang YW, Hung HC* (2009) Dual roles of Lys57 at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme. Biochem. J. 420(2):201-209. (corresponding author)
Hsieh JY, Hung HC* (2009) Engineering of the cofactor specificities and isoform-specific inhibition of malic enzyme. J. Biol. Chem. 284(7):4536-4544. (corresponding author)
Hsieh JY, Chiang YH, Chang KY, Hung HC* (2009) Functional role of fumarate site Glu59 involved in allosteric regulation and subunit-subunit interaction of human mitochondrial NAD(P)+-dependent malic enzyme. FEBS J. 276(4):983-994. (corresponding author)
Hsieh JY, Liu GY, Hung HC* (2008) Influential factor contributing to the isoform-specific inhibition by ATP of human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of the nucleotide binding site Lys346. FEBS J. 275(21):5383-5392. (corresponding author)
Hsu PC, Hung HC, Liao YF, Liu CC, Tsay GJ, Liu GY (2008) Ornithine Decarboxylase Attenuates Leukemic Chemotherapy Drugs-Induced Cell Apoptosis and Arrest in Human Promyelocytic HL-60 Cells. Leukemia Research 32(10):1530-1540.
Liao YF, Hung HC, Hsu PC, Kao MC, Hour TC, Tsay GJ, Liu GY (2008) Ornithine decarboxylase interferes within macrophage-like differentiation and matrix metalloproteinase-9 activation signaling by tumor necrosis factor alpha via NF-kB. Leukemia Research 32(7):1124-1140.
Liao YF, Hung HC, Hour TC, Hsu PC, Kao MC, Tsay GJ, Liu GY (2008) Curcumin induces apoptosis through ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells. Life Sciences 82(7-8):367-375.
Su KL, Wen TH, Chou CY, Chang GG, Liu GY, Hung HC* (2007) Structural variation manipulates the differential oxidative susceptibility and conformational stability of apolipoprotein E isoforms. Proteins: Struc. Funct. Bioinform. 68(1):363-374. (corresponding author)
Hung HC*, Lin CY, Liao YF, Hsu PC, Tsay GJ, Liu GY (2007) The functional haplotype of peptidylarginine deiminase IV (S55G, A82V and A112G) associated with susceptibility to rheumatoid arthritis dominates apoptosis of acute T leukemia Jurkat cells. Apoptosis 12(3):475-487.(corresponding author)
Liu GY, Liao YF, Hsu PC, Chang WH, Hsieh MC, Lin CY, Hour TC, Kao MC, Tsay GJ, Hung HC* (2006) Antizyme, a natural ornithine decarboxylase inhibitor, induces apoptosis of haematopoietic cells through mitochondrial membrane depolarization and caspases’ cascade. Apoptosis 11(10):1773-1788. (corresponding author)
Hsieh JY, Liu GY, Chang GG, Hung HC* (2006) Determinants of the dual cofactor specificities and substrate cooperativity of human mitochondrial NAD(P)+-dependent malic enzyme: the functional roles of Glutamine 362. J. Biol. Chem. 281(32):23237-23245. (corresponding author)
Hsu PC, Hour CT, Liao YF, Hung YC, Liu CC, Chang WH, Kao MC, Tsay GJ, Hung HC*, Liu GY (2006) Increasing Ornithine Decarboxylase Activity Is Another Way of Prolactin Preventing Methotrexate-Induced Apoptosis: CROSSTALK BETWEEN ODC AND BCL-2. Apoptosis 11(3):389-399.
Liu GY, Liao YF, Chang WH, Liu CC, Hsieh MC, Hsu PC, Tsay GJ, Hung HC* (2006) Overexpression of peptidylarginine deiminase IV features in apoptosis of haematopoietic cells. Apoptosis 11(2):183-196. (corresponding author)
Liao YF, Hsieh HC, Liu GY, Hung HC* (2005) A Continuous Spectrophotometric Assay Method for Peptidylarginine Deiminase Type 4 Activity. Anal. Biochem. 347(2):176-181. (corresponding author)
Hung HC*, Chien YC, Hsieh JY, Chang GG, Liu GY (2005) The Functional Roles of ATP Binding Residues in the Catalytic Site of Human Mitochondrial NAD(P)+-Dependent Malic Enzyme. Biochemistry 44(38):12737-12745. (corresponding author)
Hung HC*, Kuo MW, Chang GG, Liu GY (2005) Characterization of the functional role of allosteric site Asp102 in the regulatory mechanism of human mitochondrial NAD(P)+-dependent malic enzyme. Biochem. J. 392(Pt 1):39-45. (corresponding author)
Huang CC, Hsu PC, Hung YC, Liao YF, Liu CC, Hour TC, Kao MC, Tsay GJ, Hung HC*, Liu GY (2005) Ornithine decarboxylase prevents methotrexate-induced apoptosis by reducing intracellular reactive oxygen species production. Apoptosis 10(4):895-907. (corresponding author)
Liao YF, Chang WH, Tsay GJ, Hour TC, Hung HC*, Liu GY (2005) The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases’ cascade. Life Sciences 77(6):707-719. (corresponding author)
Liu GY, Hung YC, Hsu PC, Liao YF, Chang WH, Tsay GJ, Hung HC* (2005) Ornithine decarboxylase prevents tumor necrosis factor alpha-induced apoptosis by decreasing intracellular reactive oxygen species. Apoptosis 10(3):569-581. (corresponding author)
Hsu WC, Hung HC, Tong L, Chang GG (2004) Dual Functional Roles of ATP in Human Mitochondrial Malic Enzyme. Biochemistry 43(23):7382-7390.
Kuo CW, Hung HC, Tong L, Chang GG (2004) Metal-Induced Reversible Structural Interconversion of Human Mitochondrial NAD(P) -Dependent Malic Enzyme. Proteins: Struc. Funct. Bioinform. 54(3):404-411.
Hung HC, Chen YH, Liu GY, Lee HJ, Chang GG (2003) Equilibrium Protein Folding-Unfolding Process Involving Multiple Intermediates. B. Math. Biol. 65(4):553-570. (first author)
Yang Z, Zhang H, Hung HC, Kuo CC, Tsai LC, Yuan HS, Chou WY, Chang GG, Tong L (2002) Structural studies of the pigeon cytosolic NADP+-dependent malic enzyme. Protein Sci. 11(2):332-341.
Hung HC, Chang GG (2001) Multiple unfolding inetrmediates of human placental alkaline phosphatase in the equilibrium urea denaturation. Biophys. J. 81(6):3456-3471. (first author)
Hung HC, Chang GG (2001) Differentiation of the slow binding mechanism for magnesium ion activation and zinc ion inhibition of human placental alkaline phosphatase. Protein Sci. 10(1):34-45. (first author)
Chou WY, Kuo CC, Hung HC, Huang TM, Chang GG (2001) Metal binding site of pigeon liver malic enzyme. J. Med. Sci. 21:201-206.
Hung HC, Chang GG, Yang Z, Tong L (2000) Slow binding mechanism of malic enzyme: A general case. Biochemistry 39(46):14095-14102. (first author)
Yang Z, Batra R, Floyd DL, Hung HC, Chang GG, Tong L (2000) Potent and competitive inhibition of malic enzyme by lanthanide ions. Biochem. Biophys. Res. Commun. 274(2):440-444.
Chang GG, Huang TM, Hung HC* (2000) Reverse micelles as life-mimicking systems. Proc. Natl. Sci. Counc. Repub. China B 24(3):89-100.
Hung HC*, Huang TM, Chang GG (1999) Partitioning of 4-nitrophenol in Aerosol-OT Reverse micelles. J. Chem. Soc. Perkin Trans. 2:2177-2182. (first author)
Hung HC*, Chang GG (1998) Biphasic denaturation of human placental alkaline phosphatase in guanidinium chloride. Proteins: Struc. Funct. Genet. 33(1):49-61. (first author)
Hung HC*, Huang TM, Chang GG (1998) Inhibitory effects of magnesium ion on the human placental alkaline phosphatase-catalyzed reaction in a reverse micellar system. J. Protein Chem. 17(2):99-106. (first author)
Huang TM, Hung HC*, Chang TC, Chang GG (1998) Solvent kinetic isotope effects on the placental alkaline phosphatase in reverse micelles. Biochem. J. 330 (Pt1):267-275.
Hung HC*, Huang TM, Chang GG (1997) Reverse micelles as model system to study leaving group effects on alkaline phosphatase-catalysed hydrolysis. J. Chem. Soc. Perkin Trans. 2:2757-2760. (first author)
