Satange R‡, Chang CC‡, Li LY, Lin SH, Neidle S, Hou MH. Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects. Nucleic Acids Res. 2023 :gkad156. doi: 10.1093/nar/gkad156.
Huang FL, Yu SJ, Liao EC, Li LY, Shen PW, Li CL. Niclosamide suppresses T‑cell acute lymphoblastic leukemia growth through activation of apoptosis and autophagy. Oncol Rep. 2022;47(2):30. doi: 10.3892/or.2021.8241.
Lin PY, Yang D, Chuang CH, Lin H, Chen WJ, Chen CY, Chuang TJ, Lai CY, Li LY, Schuyler SC, Lu FL, Liu YC, Lu J. Comparative Analyses of Single-Cell Transcriptomic Profiles between In Vitro Totipotent Blastomere-like Cells and In Vivo Early Mouse Embryonic Cells. Cells. 2021;10(11):3111. doi: 10.3390/cells10113111.
Nguyen MT, Lin CH, Liu SM, Miyashita A, Ihn H, Lin H, Ng CH, Tsai JC, Chen MH, Tsai MS, Lin IY, Liu SC, Li LY, Fukushima S, Lu J, Ma N. miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma. Neoplasia. 2020; 22 (12): 789-799.
Chen YH, Chung CC, Liu YC, Lai WC, Lin ZS, Chen TM, Li LY*, Hung YY1 and HDAC9c transcriptionally regulate p38-mediated mesenchymal stem cell differentiation into osteoblasts. Am J Cancer Res. 2018;8(3):514-525.
Lo WJ, Lin CL, Chang YC, Bai LY, Lin CY, Liang JA, Li LY, Chao LM, Chiu CF, Chen CM, Yeh SP. Total body irradiation tremendously impair the proliferation, differentiation and chromosomal integrity of bone marrow-derived mesenchymal stromal stem cells. Annals of Hematology. 2018;97(4):697-707
Lin PH, Li HY, Fan SC, Yuan TH, Chen M, Hsu YH, Yang YH, Li LY, Yeh SP, Bai LY, Liao YM, Lin CY, Hsieh CY, Lin CC, Lin CH, Lien MY, Chen TT, Ni YH, Chiu CF. A targeted next-generation sequencing in the molecular risk stratification of adult acute myeloid leukemia: implications for clinical practice. Cancer Medicine. 2017;6(2):349-360
Y-H. Chen, Y-C Liu, C-J Chung, S-P Yeh, J Hsu, M-C Hung, H-L Su and L-Y Li*. 2016. EZH2 and HDAC9c regulate age-dependent mesenchymal stem cell differentiation into osteoblasts and adipocytes., Stem Cells . (SCI)
Li, C-W., Xia, W., Lim, S-O., Hsu, Jennifer L., Huo, L., Wu, Y., Li, L-Y., Lai, C-C.,Chang, S-S., Hsu, Y-H., Sun, H-L., Kim, J., Yamaguchi, H., Lee, D-F., Wang, H., Wang, Y., Chou 2016/03 AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation., Cancer Research, . vol.76, pp.1451-1462,. (SCI)
P-H Lin, W-H Kuo, A-C Huang, Y-S Lu, C-H Lin, S-H Kuo, M-Y Wang, C-Y Liu, F T-F Cheng, M-H Yeh, H-Y Li, Y-H Yang, Y-H Hsu, S-C Fan, L-Y Li, S-L Yu, K-J Chang,P-L Chen, Y-H Ni, C-S Huang. 2016/02 Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer, Oncotarget, . vol.7, pp.8310-8320. (SCI)
Ko HW, Lee HH, Huo L, Xia W, Yang CC, Hsu JL, Li LY, Lai CC, Chan LC, Cheng CC, Labaff AM, Liao HW, Lim SO, Li CW, Wei Y, Nie L, Yamaguchi H, Hung MC 2016 GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers,Oncotarget. vol.7, pp.57131-57144. (SCI)
Dai, H-Y., Chen, H-Y., Lai, W-J., Hung, M-C., Li, L-Y.* 2015/09 Targeted expression of BikDD combined with metronomic doxorubicin induces synergistic antitumor effect through Bax activation in hepatocellular carcinoma.,Oncotarget,. vol.6, pp.23807-23819. (SCI)
Yang, C-C., Labaff, A., Wei, Y., Nie, L., Xia, W., Huo, L., Yamaguchi, H., Hsu, Y-H., Hsu, J. L., Liu, D., Lang, J., Du, Y., Lien, H-C., Li, L-Y., Deng, R., Chan, L-C., Yao, J.,Kleer, C. G., Hortobag 2015 Phosphorylation of ezh2 at t416 by cdk2 contributes to the malignancy of triple negative breast cancers. , Am J Transl Res . vol.7, pp.1009-1020. (SCI)
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Su, C-H., Hsiao, C-L., Chang, W-S., Liu, L-C., Wang, H-C., Tsai, C-W., Li, L-Y., Tsai, C-H., Bau, D-T. 2014 Evaluation of the contribution of cyclooxygenase 2 genotypes to breast cancer in Taiwan, Anticancer Res.. vol.34, pp.6711-6716. (SCI)
. Liu, Y-C., Kao, Y-T., Huang, W-K., Lin, K-Y., Wu, S-C., Hsu, S-C., Schuyler, S-C., Li,L-Y., Lu, L. F., Lu, J. 2014 CCL5/RANTES is important for inducing osteogenesis of human mesenchymal stem cells and is regulated by dexamethasone. ,Biosci Trends. . vol.8, pp.138-143. (SCI)
Chang, T-Y., Chung, C-Y., Chuang, W-M., Li, L-Y., Jeng, L-B. and Ma, W-L. 2014 Durable Expression of Minicircle DNA-Liposome-delivered Androgen Receptor cDNA in Micewith Hepatocellular Carcinoma. , BioMed Research International. vol.9, pp. 156356. (SCI)
Huo, L., Li, C-W., Huang, T-H., Lam, Y. C., Xia, W., Tu, C., Chang, W-C., Hsu, J. L., LeeD-F., Nie, L., Yamaguchi, H., Wang, Y., Lang, J., Li, L-Y., Chen, C-H., Mishra, L. and,Hung, M-C. 2014 Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells,Am J Transl Res. vol.6, pp.649-663. (SCI)
Chou, R-H., Wang, Y-N., Hsieh, Y-H., Li, L-Y., Xia, W., Chang, W-C., Chang, L-C., Cheng, C-C., Lai, C-C., Hsu, J. L., Chang, W-J., Chiang, S-Y., Lee, H-J., Liao, H-W.,Chuan 2014 EGFR modulates DNA synthesis and repairs through Tyr phosphorylation of Histone H4. ,Dev Cell . vol.30, pp.224-237. (SCI)
Li, L-Y.*. 2014 EZH2: novel therapeutic target for human cancer. , BioMedicine,. vol.4, pp.1-6. (SCI)
Chang, W-S., Lin, S-S., Li, F-J., Tsai, C-W., Li, L-Y., Lien, C-S., Liao, W-L., Wu, H-C.Tsai, C-H., Shih, T-C., Bau, D-T. , 2013 Significant Association of Caveolin-1 (CAV1) Genotypes with Upper Urothelial Tract Cancer. ,Anticancer Res. . vol.33, pp.4907-4912. (SCI)
. Lin, P-H., Lin, C-C., Yang, H-I., Li, L-Y., Bai, L-Y., Chiu, C-F., Liao, Y-M., Lin, C-Y.,Hsieh, C-Y., Lin, C-Y., Ho, C-M., Yang, S-F., Peng, C-T., Tsai, F-J., Yeh, S-P. 2013 Prognostic impact of allogeneic hematopoietic stem cell transplantation for acute myeloid leukemiapatients with internal tandem duplication of FLT3. ,Leukemia Research,. vol.37, pp. 287-292. (SCI)
Lin, P-H., Yeh, M-H., Liu, L-C., Chen, C-J., Tsui, Y-C., Su, C-H., Wang, H-C., Liang, J-A., Chang, H-W., Wu, H-S., *Li, L-Y. and Chiu, C-F. 2013 Clinical and pathologic risk factors of tumor recurrence in patients with node-negative early breast cancer after mastectomy. ,Journal of Surgical Oncology,. vol.108, pp.352-7. (SCI)
Chen, Y-H., Hung, M-C. and Li, L-Y.*. 2012 EZH2: a pivotal regulator in controlling cell differentiation., Am J Transl Res . vol.4, pp.364-375. (SCI)
. Liu, M., Lee, D-F., Chen, C-T., Yen, C-J., Li, L-Y.*, Lee, H-J., Chang, C-J., Chang, W-C.,Hsu, J-M., Kuo, H-P., Xia, W., Wei, Y., Chiu, P-C., Chou, C-K., Du, Y., Dhar, D., Karin,M., Chen, C-H. 2012 IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression., Molecular Cell. vol.45, pp.171-184. (SCI)
Song, H., Li, C-W., LaBaff, A. M., Lim, S-O., Li, L-Y., Kan, S-F., Chen, Y., Zhang, K., Lang, J-Y., Xie, X., Wang, Y., Huo, L-F., Hsu, S-C., Chen, X-M., Zhao, Y-M. and HungM-C. , 2011 Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors., Biochem. Biophys. Res. Commun.. vol.404, pp.68-73. (SCI)
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Cai, C., Li, H., Yen, C-J., Kuo, H-P., Lee, D-F., Lang, J., Huo, L., Cheng, X., Chen, Y-J.,Li, C-W., Jeng, L-B., Hsu, J. L., Li, L-Y., Tan, A., Curley, S. A., Ellis, L. M., Dubois, R. N. 2011 APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis., J Clin Invest.. vol.121, pp.4526-4536. (SCI)
Wei, Y., Chen, Y-H., Li, L-Y.*, Lang, J., Yeh, S-P., Shi, B., Yang, C-C., Yang, J-Y., Lin,C-Y., Lai, C-C. and Hung, M-C. 2011 CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymalstem cells. ,Nature Cell Biology. vol.13, pp.87-94. (SCI)
Chen, Y-H., Yeh, F-L., Yeh, S-P., Ma, H-T., Hung, S-C., Hung, M-C. and Li, L-Y.* 2011 MITR is a switch that promotes osteogenesis and inhibits adipogenesis of mesenchymal stemcells by inactivating PPARγ-2. ,Journal of Biological Chemistry. vol.286, pp.10671-10680. (SCI)
Li, L-Y.*, Dai, H-Y., Yeh, F-L., Kan, S-F., Lang, J-Y., Hsu, J-L., Jeng, L-B., Chen, Y-H., Sher, Y-P., Lin, W-C. and Hung, M-C. 2011 Targeted hepatocellular carcinoma proapoptic BikDD gene therapy.,Oncogene. vol.30, pp.1773-83. (SCI)
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Lee, D-F., Kuo, H-P., Liu, M., Chou, C-K., Xia, W., Du, Y., Shen, J., Chen, C-T., Huo,L., Hsu. M-C., Li, C-W., Ding, Q., Liao, T-L., Lai, C-C., Lin, A-C., Chang, Y-H., Tsai, S-F., Li, L-Y. and Hung, 2009 KEAP1 E3 ligase-mediated downregulation of NF-κB signaling by targeting IKKβ.,Molecular Cell . vol.36, pp.131-140. (SCI)
Sher, Y-P., Tzeng, T-F., Kan, S-F., Hsu, J., Xie, X., Han, Z., Lin, W-C., Li, L-Y.* and Hung, M-C. 2009 Cancer targeted gene therapy of BikDD inhibits orthotopic lung cancer growth and improves long-term survival. , Oncogene . vol.28, pp.3286-3295. (SCI)
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. Ding, Q., He, X., Hsu, J-M., Xia, W., Chen, C-T., Li, L-Y., Lee, D-F., Liu, J-C., Zhong, Q.,Wang, X. and Hung, M-C. 2007 Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. , Molecular and Cellular Biology . vol.27, pp.4006-4017. (SCI)
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