葛其梅 - 教授
葛其梅 教授 繁體中文 English
專任教師
生理
04-22840416#715、716

腦缺血病理機制的探討、肺癌細胞抗藥性的研究、學習/記憶的機制探討、 中樞神經系統與免疫系統的調控機制探討

學歷

畢業學校 主修學門系所 學位 時期
美國阿拉巴馬大學伯明罕分校 生物系 博士 1989.01-1992.12

經歷 / 榮譽

經歷

服務機關 服務部門 職稱 時期
國立中興大學 生命科學系 教授 2005.02-迄今
國立中興大學 生命科學系 副教授 2002.08-2005.01
國立中興大學 動物學系 副教授 1996.08-2002.07

榮譽

年份

標題

2008.09

96學年特優導師

2006.05

94學年度教學特優教師獎

研究方向

研究興趣
1 由免疫及神經調控的角度探討腦缺血,肺癌,及急性肺受損等疾病的成因及治療。
2 評估制約性免疫反應(自然殺手細胞)的提升對小鼠體內腫瘤細胞的抑制效益

研究主題
1 腦缺血病理機制之探討
2 非小細胞肺癌抗藥機轉之探討
3 發炎反應與急性肺受損相關性之探討
4 制約性免疫活性的提升在腫瘤治療上之應用

目前研究計畫
1 瘦素如何抑制嗜中性白血球進入缺血腦組織之機轉探討(國科會, 2010.08-2013.07)
2 PPAR-gamma對非小細胞肺癌細胞中脂肪體及發炎因子生成的調控(榮興計畫, 2013.01-2013.12)
3 PPAR-gamma對腫瘤細胞之肺移轉及肺組織發炎的調控(台中榮總院內計畫, 2013.01-2013.12)
4 ALDH3A1如何幫助非小細胞肺癌(H460細胞)對抗TGF-beta所誘發之氧化壓力及生長抑制性(榮興計畫, 2012.01-2012.12)
5 評估高壓氧處理(HBO)對非小細胞肺癌(H460及CH27)之生長及缺氧所致之抗藥性是否具抑制性療效(台中榮總院內計畫, 2011.01-2011.12)
6 LRP及MRP蛋白在H460細胞的高抗藥性生成過成中扮演的角色及缺氧和珈瑪次亞麻油酸對其之調控(台中榮總院內計畫, 2010.01-2010.12)

研究室人員

博士班
陳有倫

碩士班
洪躍聞、林庭安、廖麗雅

期刊論文

 
Shu-Chung Hsieh, Chi-Hao Wu, Chun-Chi Wu, Jung-Hsing Yen, Mei-Chun Liu, Chi-Mei Hsueh*, Shih-Lan Hsu 2014 Gallic acid selectively induces the necrosis of activated hepatic stellatecells via a calcium-dependent calpain I activation pathway,Life Sci. 102:. pp. 55-64. (SCI)
Chi-Chih Cheng, Chi-Mei Hsueh, Chiu-Yuan Chen, Tzu-Hsiu Chen, Shih-Lan Hsu 2013 Interleukin-6 upregulates paraoxonase 1 gene expression via an AKT/NF-jB-dependent pathway, Biochemical and Biophysical Research Communications, 437:. pp. 55-61. (SCI)
Yeh, C-H, Hsieh, M-T, Hsueh, C-M, Wu, C-R, Huang, Y-C, Liao, J-W, Chow, K-C. 2012 Therapeutic effect of Yi-Chi-Tsung-Ming-Tang on amyloid β1-40 -induced Alzheimer's disease-like phenotype via an increase of acetylcholine and decrease of amyloid β,Evidence-Based Complementary and Alternative Medicine. 2012: 414536. (SCI)
Cheng, C-C, Wu, L-C, Lai, J-M, Chen, C-T, Hsueh, C-M*, Hsu, S-L*. 2012 Ethanol extract of Graptopetalum paraguayense upregulates paraoxonase 1 gene expression via an AKT/NF-κB-dependent pathway,The American Journal of Chinese Medicine, 40: . pp.357–372. (SCI)
Lin, L-C, Hsu, S-L, Wu, C-L, Liu, W-C, Hsueh, C-M*. 2011 Peroxisome proliferator-activated receptor γ (PPARγ) plays a critical role in the development of TGFβ resistance of H460 cell,Cell Signal. 23: . pp.1640–1650. (SCI)
Cheng, C-C, Hsueh C-M, Liang, K-W, Ting, C-T, Wen, C-L, Hsu, S-L. 2011 Role of JNK and c-Jun signaling pathway in regulation of human serum paraoxonase 1 gene transcription by berberine in human HepG2 cells, Eur J of Pharm 650. pp.519–525. (SCI)
Wang, C-H., Wang, W-T., Cheng, S-Y., Hung, W-T., Wu, T-L., Hsueh, C-M.* 2010 Leptin and interleukin-1beta modulate neuronal glutamate release and protect against glucose-oxygen-serum deprivation, Curr Neurovasc Res. 7(3):. pp.223-37. (SCI)
Lin, S-Y., Hsueh, C-M., Yu, S-L., Su, C-C., Shum, W-Y., Yeh, K-C., Chang, G-C., Chen, J-J. 2010 HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma,Nucleic Acids Res. 38. pp.6148-6158. (SCI)
Cheng, Y-J, Jiang, H-S., Hsu, S-L., Lin, L-C., Wu, C-L., Ghanta, V.K. and Hsueh, C-M.* 2010 XIAP-mediated protection of H460 lung cancer cells against cisplatin,Eur. J. Pharmacol. 627. pp.75-84. (SCI)
Chieh-Liang Wu, Liang-Yi Lin, Jyh-Shyue Yang, Ming-Cheng Chan, Chi-Mei Hsueh 2009 Attenuation of Lipopolysaccharide-induced acute lung injury with IL-10 post-treatment Respirology, 14:,pp.511-521. (SCI)
Chen-Hsuan Wang, Wen-Jane Lee, Vithal K. Ghanta, Wei-Ti Wang, Shu-Yun Cheng, Chi-Mei Hsueh 2009 Molecules involve in the self-protection of neurons against glucose-oxygen-serum deprivation (GOSD)-induced cell damage,Brain Res. Bulletin 79. pp.169-176. (SCI)
Chieh-Liang Wu, Liang-Yi Lin, Hsueh-Mei Yeh, Ming-Cheng Chan, Chih-Hsueh Yang, Chi-Mei Hsueh* 2009 Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent,SHOCK, 32(3):. pp.276-285. (SCI)
Lin, Li-Chiung, Hsu, Shih-Lan, Wu, Chieh-Liang, Liu, Wen-Chun, Chiu Hsiao-Ting and Hsueh, C.M.* 2009 Peroxisome proliferator-activated receptor (PPAR)-gamma is responsible for TGF-beta-induced epithelial mesenchymal transition (EMT) and tumor invasion of NSCLC cells (H460).,ECCO15-34th ESMO Multidisciplinary Congress. Sept 20-24, 2009; Berlin, Germany. . (SCI)
Wang, C-H, Lee, W-J; Ghanta, V.K., Wang, Wei-Ti; Cheng, S-Y, Hsueh, C-M.* 2009 Molecules involve in the self-protection of neurons against glucose-oxygen-serum deprivation (GOSD)-induced cell damage,Brain Res Bulletin. 79. pp.169-176. (SCI)
Liang, K-W, Yin S-C, Ting, C-T, Lin S-J, Hsueh, C.M., Chen, C-Y, Hsu, S-L. 2008 Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells,Eur J Pharmacol. 590. pp.343-354.
Chu, L-F, Wang, W-T, Ghanta V.K., Lin, C-H, Chiang, Y-Y, Hsueh, C.M.* 2008 Ischemic brain cell-derived conditioned medium protects astrocytes against ischemia through GDNF/ERK/NF-kB signaling pathway,Brain Res. 1239. pp.24-35. (SCI)
Yun-Chih Hsieh, Shur-Jong Hsieh, Yuan-Shiun Chang, Chi-Mei Hsueh, and Shih-Lan Hsu. 2007 The lipoxygenase inhibitor, baicalein, modulates cell adhesion and migration by up-regulation of integrins and vinculin in rat heart endothelial cells,Br J Pharmacol. 151. pp.1235-1245 . (SCI)
Lin, C.H., Cheng, F-C., Lu, Y.Z., Chu, L.F., Wang, C.H., Hsueh, C.M. 2006 Protection of ischemic brain cells is dependent on astrocyte-derived growth factors and their receptors, Exp. Neurol. 201. pp.225-233. (SCI)
Lin, C.H., Lu, Y.Z., Cheng, F-C., Chu, L.F., Hsueh, C.M. 2005 Bax-regulated mitochondria-mediated apoptosis is responsible fro the in vitro ischemia induced neuronal cell death of Sprague Dawley rat,Neurosci. Lett. 387. pp.22-27. (SCI)
Lu, Y.Z., Lin, C.H., Cheng, F.C., Hsueh, C.M* 2005 Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia,Neurosci. Lett. 373. pp.159-164. (SCI)
Chao, H.J., Hsu, Y.C., Yuan, H.P., Jiang, H.S., Hsueh, C.M* 2005 The conditioned enhancement of neutrophils activity is catecholamine dependent. J,Neuroimmunol. 1 J. Neuroimmunol. 158. pp.159-169. (SCI)
Lee, G.A., Lin, C-H., Jiang, H-H., Chao, H-J., Wu, C-L., and Hsueh, C.M* 2004 Microglia-derived glial cell line-derived neurotrophic factor could protect Sprague Dawley rat astrocyte from in vitro ischemia-induced damage,Neurosci. Lett. 356. pp.111-114. (SCI)
Hsueh, C-M*., Kuo, J-S., Chen, S-F. 2003 Ischemia/reperfusion-induced changes of hypothalamic-pituitary adrenal (HPA) activity is opioid related in Sprague-Dawley rat,Neurosci. Lett. 349. pp.155-158. (SCI)
Hsueh, C-M., Chen, S-F., Lin, R-J., and Chao, H.-J. 2002 Cholinergic and serotonergic activities are required in triggering conditioned NK cell response,J. Neuroimmunology. 123. pp.102-111. (SCI)
Hsueh, C-M*., Chen, S-F., Lin, R-J., Chao, H-J. 2002 Cholinergic and serotonergic activities are required in triggering conditioned NK cell response,J. Neuroimmunol. 123. pp.102-111. (SCI)
Kuo, J-S., Chen, S-F., Huang, H-J., Yang, C-S., Tsai, P-J, and Hsueh, C-M* 2001 The involvement of glutamate in recall of the conditioned NK cell response, J. Neuroimmunol. 118. pp.245-255. (SCI)
Kuo, J-S., Chen, S-F., Huang, H-J., Yang, C-S., Tsai, P-J., Hsueh, C-H*. 2001 The involvement of glutamate in recall of the conditioned NK cell response, J. Neuroimmunol. 118. pp.245-255 . (SCI)
Hsueh, C-M., Kuo, J-S., Chen, S-F., Huang, H-J., Cheng, F-C., Chung, L-J., and Lin, R-J. 1999 Involvement of catecholamines in recall of the conditioned NK cell response, J. Neuroimmunology. 94. pp.172-181. (SCI)
Hiramoto, R.N., Rogers, C.F., Demissie, S., Hsueh, C-M., Hiramoto, N.S., Lorden, J.F., and Ghanta, V.K. 1997 Psychoneuroendocrine immunology site of recognition, Learning and memory in the immune system and th Intern. J. Neurosci. 92(3-4). pp.259-285. (SCI)
Hsueh, C-M., Chen, S-F., Huang, H-J., Ghanta, V.K., and Hiramoto, R.N. 1996 Activation of the mu-opioid receptors are required for the conditioned enhancement of NK cell activi Brain Res. 737,pp. 263-268. (SCI)
Hsueh, C-M., Chen, S-F., Ghanta, V.K., and Hiramoto, R.N. 1996 Involvement of cytokine gene expression in the age-dependent decline of NK cell response,Cell. Immunol. 173. pp.221-229. (SCI)
Hiramoto, R.N., Rogers, C., Demissie, S., Hsueh, C-M., Hiramoto, N., Lorden, J., Ghanta, V.K., 1996 The use of conditioning to probe for CNS pathways that regulate fever and NK cell activity. Intern., J. Neurosci. 84(1-4). pp.229-245. (SCI)
Hsueh, C-M., Chen, S-F., Ghanta, V.K., and Hiramoto, R.N. 1995 Expression of the conditioned NK cell activity is b-endorphin dependent,Brain Res. 678. pp.76-82.. (SCI)
Ghanta, V.K., Rogers, C.F., Hsueh, C-M., Demissie, S., Lorden, J.F., Hiramoto, N.S., Hiramoto, R.N. 1994 Role of arcuate nucleus of the hypothalamus in the acquisition of association memory between the CS J,Neuroimmunol. 50. pp.109- 114. (SCI)
Hsueh, C-M., Rogers, C.F., Hiramoto, R.N., and Ghanta, V.K. 1994 Effect of dexamethasone on conditioned enhancement of natural killer cell activitv,NeurolmmunoModulation. 1. pp.370-376. (SCI)
Hsueh, C-M., Hiramoto, R.N., and Ghanta, V.K. 1994 Efferent signals responsible for the conditioned enhancement of natural killer cell response, NeuroImmunoModulation. 1. pp. 74-81. (SCI)
Hiramoto, R.N., Ghanta, V.K., Solvason, H.B., Lorden, J.F., Hsueh, C-M., Rogers, C.F., Demissie, S. and Hiramoto, N.S. 1993 Identification of specific pathways of communication between the CNS and NK cell system,Life Sci. 53. pp. 527-540. (SCI)
Hiramoto, R.N., Hsueh, C-M., Rogers, C.F., Demissie, S., Hiramoto, N.S., Soong, S-J., Ghanta, V.K. 1993 Conditioning of the allegeneic cytotoxic Iymphocyte response,Pharmac. Biochem. Behav. 44. pp. 275-280. (SCI)
Rogers, C.F., Ghanta V.K., Hsueh, C-M., Hiramoto, N.S., Hiramoto, R.N., 1992 The direction of the conditioned NK cell response can be re directed with indomethacin and/or handli Int,J. Neurosci. 67. pp.229 239. (SCI)
Solvason, H.B., Ghanta, V.K., Soong, S-J., Rogers, C.F., Hsueh, C-M., Hiramoto, N.S., and Hiramoto, R.N 1992 A simple single trial learning paradigm to condition the natural killer cell activity, Proc. Soc. Exp. Biol. Med. 199. pp.199-203. (SCI)
Hiramoto, R.N., Ghanta, V.K., Lorden, J.F., Solvason, H.B.,Soong, S-J., Rogers, C.F., Hsueh, C-M., Hiramoto, N.S. 1992 Conditioning of the NK cell response: effects of inter-stimulus intervals and evidence for for long Prog,NeuroEndocrinImmunol. 5. pp.13-20. (SCI)
Hsueh, C-M., Lorden, J.F., Hiramoto, R.N., Ghanta, V.K. 1992 Acquisition of enhanced natural killercell activity under anesthesia. LifeSci,50:2067-2 1992 Acquisition of enhanced natural killercell activity under anesthesia. Life Sci. 50. pp.2067-2704.
Hsueh, C-M., Hiramoto, R.N., Ghanta, V.K. 1992 The central effect of methionine-enkephalinon NK cell activity,Brain Res. 578. pp.142-148. (SCI)
Rogers, C.F., Ghanta, V.K., Hsueh, C-M., Hiramoto, N.S., Hiramoto, R.N. 1992 Indomethacin and sodium carbonate effects on conditioned fever and NK cell activity. Pharmacol,Biochem. Behav. 43. pp.417-422. (SCI)
Ghanta, V.K., Rogers, C.F., Hsueh, C-M., Hiramoto, N.S., Soong, S-J., and Hiramoto, R.N. 1991 In Vivo enhancement of NK cell activity with met-enkephalin and glycyl-glutamine: Their possible rol Int,J. Neurosci. 61. pp.135-143. (SCI)

研討會論文

 
Yueh-Wen, Hung(洪耀聞), Tsung-Ying Yang(楊宗穎),Yu-Lun Chen(陳有倫), Li-Chiung Lin (林麗瓊), Chi-Mei Hsueh*(葛其梅) 2014 Role of PPAR in promotion of adiposome formation and inflammatroy mediator production in non-small cell lung cancers,中區八大院校暨台中榮總合作研究計畫聯合成果發表會. (台中,台灣).
Lin, L-C, Chen, K-C, Li, Y-F and Hsueh, C-M* 2013 The role of ALDH3A1 in the protection of NSCLCs (H460 cells) from TGF-beta-mediated oxidative stress and growth inhibition ,101年度中區院校暨台中榮總合作研究計畫聯合成果發表會. 台中, 台灣.
Li-Chiung Lin (林麗瓊), Kun-Chieh Chen (陳焜結), Yi-Fang Li(李依芳),Chi-Mei Hsueh*(葛其梅) 2013 The role of ALDH3A1 in the protection of NSCLCs (H460 cells) from TGF-mediated oxidative stress and growth inhibition ,中區八大院校暨台中榮總合作研究計畫聯合成果發表會. (台中,台灣).
Pei-Chen Hsu (許珮甄), Chi-Mei Hsueh*(葛其梅) 2013 How leptin regulates the activities of endothelial cells to prevent the neutrophil infiltration into ischemic brai., 中華民國基礎神經科學學會2013年學術年會. (台北,台灣).
Chang-Hung Lin(林昶鴻), Chi-Mei Hsueh* (葛其梅) 2013 Leptin and ACMs can down regulate the permeability or stimulate the tube formation of vascular endothelial cells under ischemic condition, 中華民國基礎神經科學學會2013年學術年會. (台北,台灣) .
Kang-Yun Lu (陸康芸), Chi-Mei Hsueh* (葛其梅) 2013 Leptin may act through autophagy inhibition to reduce the ROS release from GOSD-treated microglia,中華民國基礎神經科學學會2013年學術年會. (台北,台灣) .
Ting-Xuan Wei (魏廷軒), Chi-Mei Hsueh* (葛其梅) 2013 PPAR-γ can stimulate adiposome formation and ROS release from microglia under the ischemic stress,中華民國基礎神經科學學會2013年學術年會. (台北,台灣) .
Cheng-Hsun Wu (吳承勳), Chi-Mei Hsueh*(葛其梅). 2013 Brain infiltration of neutrophils may aggravate the ischemic-induced brain infarction through the release of inflammatory mediators,中華民國基礎神經科學學會2013年學術年會. (台北,台灣) .
Yu-Lun Chen (陳有倫), Chi-Mei Hsueh*(葛其梅) 2013 Hypoxia can exacerbate DOX-induced cell injury in NSCLCs by suppressing the expression of MRP1 and P-gp, 台灣生物化學暨分子生物學學會2013冬令營 . (台中,台灣) .
Lin, L-C, Hsu, S-L, Wu, C-L and Hsueh, C-M.* 2012 Peroxisome proliferator-activated receptor gamma (PPAR-gamma) reveals a critical role in promoting the TGF-beta-induced EMT and metastasis of non-small cell lung cancer cell (H460). ,American Association of Cancer Research Annual Meeting 2012. March 31-April 04, 2012; Chicago, USA. Presentation.
Cheng, S-Y, Wang, C-H, Chang, A-J, Hsu, P-C and Hsueh, C-M* 2011/05 The pathophysiological role of neutrophil in ischemic brain. XXXVth International Symposium on Cerebral Blood Flow,Metabolism and Function and Xth International Conference on Quantification of Brain Function with PET. May 24-28, 2011; Barcelona, Spain .
Chen, Y-L, Chang, C-L, Lin, L-C and Hsueh, C-M*. 2011/04 Potential role of multidrug resistance associated protein (MRPs) and P-glycoprotein (P-gp) in hypoxia-induced drug resistance of non-small cell lung cancer cells,American Association of Cancer Research Annual Meeting 2011. April 2-6, 2011; Orlando, USA. Presentation.
Lin, Li-Chiung, Hsu, Shih-Lan, Wu, Chieh-Liang, Liu, Wen-Chun, Chiu Hsiao-Ting and Hsueh, C.M.* 2009/09 Peroxisome proliferator-activated receptor (PPAR)-gamma is responsible for TGF-beta-induced epithelial mesenchymal transition (EMT) and tumor invasion of NSCLC cells (H460). ,Joint ECCO15-34th ESMO Multidisciplinary Congress. Sept 20-24, 2009; Berlin, Germany. (SCI)
Hung, Wan-Ting, Wang, Chen-Hsuan, Wang, Wei-Ti, Wu, Tzu-Lien, Hsueh, C.M.*. 2009/08 Leptin-mediated brain protection against cerebral ischemia/reperfusion, The 22nd Biennial Meeting of the ISN/APSN Joint Meeting Satellite Conference. Aug 30-Sept 2, 2009; Taipei, Taiwan. .
Lin, L-C , Chiu, H-T, Liu, W-C, Cheng, Y-J and Hsueh, C.M.* 2008/04 Peroxisome proliferator-activated receptor γ disrupts transforming growth factor β-mediated cell growth inhibition in non-small cell lung cancer cells (H460) by binding to Smad3. ,American Association of Cancer Research Annual Meeting 2008. April 12-16, 2008; San Diego, USA. Presentation .
劉玟君,葛其梅 2008 PPAR-gamma (過氧化體增殖活化接受體)在非小細胞肺癌(H460細胞株)抗藥性生成過程中之重要性及作用機轉探討,中興大學生命科學系專題研究競賽展 (第一名) .
潘妍如,葛其梅. 2008 缺血神經細胞釋出液(NCM)及缺血星芒狀細胞(ACM)釋出液中ROS對缺血星芒細胞存活之影響及訊號之傳遞, 中興大學生命科學系專題研究競賽展.
王瑱瑄,李文珍,洪婉婷,鄭淑云,李芮甄,潘妍如,王偉迪,葛其梅. 2008 Effects of inflammatory factors on ischemic neurons and the application in the control of cerebral ischemia,96年度中區八大院校暨台中榮總合作研究計畫聯合成果發表會. 台中,台灣 (壁報組第八組第二名) .
李芮甄,葛其梅 2008 神經細胞釋出液中自由基對缺血微膠細胞存活之影響及角色確認, 中興大學生命科學系專題研究競賽展 .
Lin*, L.C., Cheng, Y.J., Chiu, H.T., Liu, W.J. and Hsueh, C.M.*. 2007 TGF-beta resistance of NSCLC cells (H460) is PPAR-gamma- and XIAP-dependent. Biomedical Conference,Taiwan.
Cheng, S-Y (鄭淑云), Cheng, F-C (陳甫州), Chang, C-H (張竣泓), Hung, W-T (洪婉婷), and Hsueh, C.M.*(葛其梅). 2007 Mesenchymal stem cells (MSCs)-mediated protection of the ischemic brain was not augmented by the ischemic neuron derived conditioned medium,95年度中區八大院校暨台中榮總合作研究計畫聯合成果發表會. 台中, 台灣 (壁報組第二名) .
Cheng, S-Y, Chang, C-H, Hung, W-T, Hsueh, C.M.* 2007 Cerebral ischemia induced cell migration of immunocytes and mesenchymal stem cells (23rd International Symposium on Cerebral Blood Flow,Metabolism and Function. May 20-24, 2007; Osaka, Japan) Presentation.
Cheng, S-Y, Lin, C-H, Wang, C-H and Hsueh, C.M.* 2006 Ischemic neuron-derived conditioned media protect ischemic brain in ERK and NO related manner,(The 8th International Congress of Neuroimmunology /ISNI 2006. Oct. 15-19, 2006, Nagoya, Japan) Presentation .
Lin, C.H., Lu, Y.Z., Cheng, F.C., Hsueh, C.M.*, 2005 Bax translocation plays a key role in mediating the ischemia-induced apoptosis in neuron,Annual Conference of Chinese Society of Cell and Molecular Biology. Taiwan (R.O.C.) .
Chao, H-J., Hsu, Y-C., Hsueh, C.M.* 2004 The role of catecholamines in the conditioned enhancement of neutrophils activity,The 6th Biennial Meeting of the Asian-Pacific Society for Neurochemistry/APSN 2004. Feb 4-7, 2004, Hong Kong). Presentation .

專利

 
葛其梅 2014 篩選治療肺部腫瘤候選藥物之方法,專利號碼:發明第I 431117號;中華民國;2014-2032 .
葛其梅 2014 抑制、治療肺部腫瘤與抑制發炎反應之醫藥組合物及其製備之方法, 專利號碼: 發明第I 427054號;中華民國;2014-2032.
Lin LC, Hsu SL, Hsueh CM. 2012 GW9662 inhibits tumorigenesis and inflammation,Taiwanese patent; pending number: 101102603.
Lin LC, Hsu SL, Hsueh CM 2012 Mouse model of human lung cancer,Taiwanese patent; pending number: 101102611.