林赫 - 教授
林赫 教授 繁體中文 English
專任教師
生理
04-22840416#310、311

生理學、細胞生物學、腫瘤生物學、生理藥理學、內分泌學、神經生物學

學歷

畢業學校 主修學門系所 學位 時期
國立陽明大學 生理學研究所 博士 1995 ~ 2000
私立東海大學 生物學系 學士 1991 ~ 1995

經歷 / 榮譽

經歷

服務機關 服務部門 職稱 時期
科技部 駐澳大利亞代表處 參事組長 2022.02 迄今
國立中興大學 生命科學系 系主任 2019.02 - 2022.01
國立中興大學 生命科學系 副系主任 2017.08 迄今
國立中興大學 研發處學術發展組 組長 2014.8 -2018.7
科技部 生命科學司 專題研究計畫-複審委員 2015~
國立中興大學 生命科學系 教授 2013.08 迄今
Chinese Journal of Physiology (SCI) Editorial Office Associate Editor (副主編) 2013 迄今
Pharmacologia 編輯部 編輯 2014/1 迄今
台灣內分泌及代謝學會 理事會 理事 2014/5 迄今
中國醫藥大學附設醫院 醫學研究部 顧問 2013/8 迄今
American Journal of Cancer Review 編輯部 編輯 2013/7 迄今
亞洲大學 生物科技系 合聘教授 2013/8 迄今
Evidence-based Complementary and Alternative Medicine (SCI) 編輯部 編輯 2014/12 迄今
中國生理學會 理事會 理事 2014.5 迄今
美國德州大學西南醫學中心 泌尿外科 訪問教授 2012.02 至 2013.01
Adaptive Medicine 期刊 編輯部 副主編 2011.01 迄今
台灣調適科學會 理事會 理事 2007~2009
國立中興大學 生命科學系 副教授 2009.02~2014.07
國立中興大學 生物科技發展中心研究發展組 組長 2014.2 ~ 2014.7
國立中興大學 生命科學系 助理教授 2004.10~2009.01

榮譽

年份

標題

2020

國立中興大學「特聘教授」

2018

國立中興大學「特聘教授」

2017

國立中興大學「特優導師」

2016

指導本系學生郝貞明參與科技部大專學生專題研究計畫榮獲105年度"研究創作獎"

2015

國立中興大學「優秀年輕學者獎助計畫-懷璧獎」

2013

國立中興大學傑出青年教師

2012

指導博士班學生獲得第二十屆細胞及分子生物新知研討會優秀論文獎(許馥甯)

2011

國立中興大學傑出青年教師獎

2011

指導博士班學生獲得第七屆亞太平洋生理學會大會優秀論文獎(許馥甯)及論文佳作獎(黃寶萱)

2011

指導博士班學生獲得美國細胞生物學會年會之旅行獎(許馥甯)

2010

獲邀參加"第三屆台法前鋒科學論壇國際成員養成會議"

2010

獲98年度國立中興大學建教合作計畫之"成長之星"

2010

榮獲99年度國立中興大學產學績優獎

2009

台中榮民總醫院與十大院校合作計畫優良論文

2009

國立中興大學傑出青年教師獎

2008

指導台中一中學生陳其寬獲得第七屆旺宏科學獎金牌

2008

指導本系學生楊旻修參與國科會大專學生專題研究計畫榮獲96年度"研究創作獎"

2007

國科會96年度傑出學者養成計畫

2007

台中榮民總醫院與八大院校合作計畫發表第一名

2006

指導學生獲得2006年(第21屆)生物醫學聯合年會「優秀壁報獎」 (學生: 陳疇丞)

2004

第12屆細胞及分子生物新知研討會「優秀壁報獎」

研究方向

研究興趣
1 各種腫瘤之細胞內訊息傳遞及藥物作用(包括攝護腺癌, 乳癌, 肺癌, 子宮頸癌, 膀胱癌, 甲狀腺癌等)
2 內分泌之細胞內訊息傳遞
3 探討神經分化之分子機制 (包括神經退化性疾病)

研究主題
1 癌症的致癌機轉及藥物反應
2 雄性激素生物合成機轉及受到藥物的影響

目前研究計畫
1. 科技部研究計畫(2017-2020): CDK5與有絲分裂的關係探討
2. 農委會研究計畫(2016-2017): 攝護腺肥大的藥物開發
3. 科技部龍門計畫(2014-2016): 研發可治療具抗性之攝護腺癌的新穎生物源奈米藥劑並探討其專一機制
4. 國科會專題研究計畫 (2015~2016): 探討 Cdk5蛋白激酶經由調控細胞週期抑制蛋白 p21 表現而影響乳癌細胞進展之生理機制
5. 榮總中興合作計畫(2016): 探討 Cdk5 是否可藉由調控HIF-1α而影響癌細胞之VEGF 的表現並刺激血管新生
6. 大專學生暑期研究計畫(2015~2016): 探討神經生長因子於攝護腺癌 LNCaP 細胞株中是否可透過刺激Erk-Egr-1-p35 蛋白途徑而活化 Cdk5 激酶並促進下游雄性激素受體活性及癌細胞生長

研究室人員

現任人員:
碩士級研究助理-
鄭語喬、宋軒瑋

博士班-
高暐翔, Muhammet Oner, Ayse Celik, 洪孟愉, 鄭邦廷, 李柏昕, 黃文正

碩士班
二年級: 吳雅嫻
一年級: 陳怡如

大學部-
蔡孟桓、羅意婷

獲斐陶斐會員榮譽:
2022-鄭羽辰
2021-廖婉伶、游椀媜、王和善(Prince)

離職人員:
博士後研究員-
許馥甯(Scientist, Bionova Scientific Co, USA)
林麗瓊(Postdoctoral Fellow, University of Glascow, UK)
張智翔(正瀚生技博士後研究員)
林君榕(Postdoctoral Fellow, Univeristy of Texas Southwestern Medical Center, USA)

碩士級研究助理-
黃威寰, 江明憬, 王若馨, 黎喻暄

畢業博士-
許馥甯(2011-Texas A&M博士後研究員)
蕭宏柏(2011-國家衛生研究院博士後研究員)
陳靜嫻(2011-UC Davis助理教授)
張仲達(2012-亞東醫院急診部醫師)
王心怡(台中榮民總醫院核子醫學科醫師)
林筱筠(美國中國醫藥大學博士後研究)
林育慶(2015-彰濱秀傳紀念醫院泌尿外科醫師)
李岳聰(彰濱秀傳紀念醫院副院長)
于家珩(童綜合醫院教學部主任)
賴威仲(2016-成大博士後研究員)
黃寶萱(2016-衛福部食藥署)
張瓊方(2016)
周柔君(2021)

畢業碩士-
2006: 古建得,曾群富,郭宏碩,陳疇丞
2007: 許馥甯,邱治源,吳承修
2008: 林俐伶,李冠勳,劉美芳
2009: 黃威寰,張瓊方,游舜期
2010: 江明憬,王麗娟
2011: 洪慶宗,彭裕婷,陳姿吟,林耿志
2012: 董佩綾,朱敏嘉,連傳岳,黃振權
2013: 白家明,周敬唐,李培齊
2014: 邱德桓
2015: 王若馨,高暐翔,王俊智
2016: 王建甯,王韻琪
2017: 高筱涵,林薰妤,莊家驊
2018: 張婷捷, 張智瑩
2019: 方晧, 林奇翰, 陳巧倫, 張景明
2020: 廖婉伶、游婉媜、謝丞恩
2021: 鄭語喬、鄭邦廷、劉芳伶
2022: 宋軒瑋
2023: 許瓅文、林鼎祐


大學生-
李冠勳(國科會計畫2006-中興生科所)
江明憬(國科會計畫2007-中興生科所)
楊旻修(國科會計畫創作獎2008-陽明生化所)
劉靜宜(國科會計畫2008-成大生理所)
黃寶萱(國科會計畫2009-中興生科所)
白竹君(2009)
曾百功(國科會計畫2011-中興生科所)
賴怡君(2015)
宋時瑜(2015-陽明藥理所)
陳家璋(2015-陽明生藥所)
陳一誠(2015-成大生理所)
郝貞明(科技部計畫創作獎2016-台大解剖所)
馮興凱(2017-陽明大學微免所)
陳森強(台大免疫所)
張晏慈(台大生化所)
張修維(成大生化所)
劉念慈(台大生化所)

期刊論文

 
Lin LC, Gao AC, Lai, CH*, Hsieh JT*, and Lin H* 2017/01 Induction of neuroendocrine differentiation in castration resistant prostate cancer cells by adipocyte differentiation-related protein (ADRP) delivered by exosomes.,Cancer Letters. vol.391, no.74-82. (SCI)
Chen YA, Lien HM, Kao MC, Lo UG, Lin LC, Lin CJ, Chang SJ, Chen CC, Hsieh JT*, Lin H*, Tang CH*, and Lai CH* 2017/01 Sensitization of radioresistant prostate cancer cells by resveratrol isolated from Arachis hypogaea stems.,PLoS One. vol.12, pp.e0169204. (SCI)
Huang PH, Chen MC, Peng YT, Kao WH, Chang CH, Wang YC, Lai CH, Hsieh JT, Wang JH, Lee YT, Lin E, Yue CH, Wang HY, You SC, Lin H* 2016/12 Cdk5 directly targets nuclear p21CIP1 and promotes cancer cell growth, Cancer Research . vol.76, pp.6888-6900. (SCI)
Lai CK, Chen YA, Lin CJ, Lin HJ, Kao MC, Huang MZ, Lin YH, Chiang-Ni C, Chen CJ, Lo 2016/02 Molecular mechanisms and potential clinical applications of Campylobacter jejuni cytolethal distending toxin, Frontiers in Cellular and Infection Microbiology. vol.6, no.9. (SCI)
Hsiao HB, Hsieh CC, Wu JB, Lin H, and Lin WC* 2016/02 Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells response,BMC Complementary and Alternative Medicine. vol.16, no.80. (SCI)
Huang PH, Wang HY, Huang CC, Lee YT, Yue CH, Chen MC*, Lin H* 2016 Suppression of breast cancer cell growth by Her2-reduced AR serine 81 phosphorylation, Chinese Journal of Physiology. (SCI)
Lin CJ, Lai CK, Kao MC, Wu LT, Lo UG, Lin LC, Chen YA, Lin H*, Hsieh JT*, Lai CH*, Lin 2015/06 Impact of cholesterol on disease progression,Biomedicine. vol.5, no.7. (SCI)
Yue CH, Huang CY, Tsai JH, Hsu CW, Hsieh YH*, Lin H*, Liu JY* 2015/05 MZF-1/Elk-1 complex binds to protein kinase Cα promoter and is involved in hepatocellular carcinoma,PLoS One. vol.10, no.5. (SCI)
Lin HY, Huang BR, Yeh WL, Lee CH, Huang SS, Lai CH, Lin H, and Lu DY 2014/02 Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways,Neurobiology of Aging. vol.35, no.191-202. (SCI)
Chen MC, Hsu SL, Lin H*, and Yang TY* 2014 Retinoic acid and cancer treatment,Biomedicine. vol.4, no.4, pp.22. (SCI)
Shen SC, Shen CI, Lin H, Chen CJ, Chang CY, Chen SM, Lee HC, Lai PS, and Su HL* 2014 Susceptibility of human embryonic stem cell-derived neural cells to Japanese encephalitis ,PLoS One. vol.9, no.12. (SCI)
Lin E, Chen MC, Huang CY, Hsu SL, Huang WJ, Lin MS, Wu JCH, Lin H* 2014 All-trans retinoic acid induces DU145 cell cycle arrest through Cdk5 activation,Cellular Physiology and Biochemistry. vol.33, pp.1620-1630. (SCI)
Hsu FN, Chen MC, Lin KC, Peng YT, Li PC, Lin E, Chiang MC, Hsieh JT, and Lin H* 2013 Cyclin-dependent kinase 5 modulates STAT3 and androgen receptor activation through phosphorylation of Ser727 on STAT3 on prostate cancer cells,American Journal of Physiology-Endocrinology and Metabolism. vol.305, pp.E975-E986. (SCI)
Huang PH, Huang CY, Chen MC, Lee YT, Yue CH, Wang HY, and Lin H* 2013 Emodin and aloe-emodin suppress breast cancer cell proliferation through ERα inhibition,Evidence-based Complementary and Alternative Medicine. vol.2013, pp.376123. (SCI)
Hsiao HB, Lin H, Wu JB, and Lin WC 2013 Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways,Osteoporosis International, 24. pp.1663-1676. (SCI)
Lin E, Lin H, Hung GU, Wu JCH, Hsieh HL, Lin TC, Chen CC, Wang CH, Lin MS 2013 Spontaneous rupture of the bladder after a seizure,a pitfall of diagnosis. Surgical Science, 4.
Wang HY, Lin WY, Chen MC, Lin T, Chao CH, Hsu FN, Lin E, Huang CY, Luo TY, and Lin H* 2013 Inhibitory effects of Rhenium-188-labeled Herceptin on prostate cancer cell growth,a possible radioimmunotherapy to prostate carcinoma. International Journal of Radiation Biology, 89. no.1 , pp.346-355 . (SCI)
Chen MC, Huang CY, Hsu SL, Lin E, Ku CT, Lin H*, and Chen CM* 2012 Retinoic acid induces apoptosis of prostate cancer DU145 cells through Cdk5 over-activation, ECAM, 2012: 580736 . no.1. (SCI)
Lin HY, Yeh WL, Huang BR, Lin C, Lai CH, Lin H*, and Lu DY* 2012 Desipramine protects neuronal cell death and induces heme oxygenase-1 expression in Mes23.5 dopaminergic neurons,PLoS One, 7: e50138 . (SCI)
Lin H and Wang PS 2012 Inhibitory effects of digoxin on testosterone production in rat Leydig cells,Adaptive Medicine, 4. pp.165-172 .
Chang CT, Ho TY, Lin H, Liang JA, Huang HC, Li CC, Lo HY, Wu SL, Huang YF, and Hsiang CY 2012 5-Fluorouracil induced intestinal mucositis via nuclear Factor-kappaB activation by transcriptomic analysis and in vivo bioluminescence imaging,PLoS One, 7: e31808 . (SCI)
Lee YT*, Lin H, Guo JC, Yan SL, Hou HJ, Lai YS, Liu YH, Wu HS, and Hwang MH 2012 Laparoscopy-assisted Billroth I gastrectomy for ectopic pancreas in the prepyloric region,Case Report of Gastroenterology, 6. pp.712-719 .
Hsu FN, Chen MC, Chiang MC, Lin E, Lee YT, Huang PH, Lee GS, Lin H* 2011 Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5,Journal of Biological Chemistry, 286. pp.33141-33149. (SCI)
Hsiao HB, Wu JB, Lin H, Lin WC*. 2011 Kinsenoside isolated from Anoectochilus formosanus suppresses lipopolysaccharide-stimulated inflammatory reactions in macrophages and endotoxin shock in mice,Shock, 35. pp.184-190.
Chang CT, Lin H, Ho TY, Li CC, Lo HY, Wu SL, Huang YF, Liang JA, Hsiang CY 2011 Comprehensive assessment of host responses to ionizing radiation by nuclear factor-κB bioluminescence imaging-guided transcriptomic analysis,PLoS One, 6: e23682 . pp.IF: 4.092. 14.1%. (SCI)
Hsu FN, Yang MS, Lin E, Tseng CF, Lin H*. 2011 The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells,American Journal of Physiology-Endocrinology and Metabolism, 300. pp.E902-E908 .
Lien HM, Kuo PT, Huang CL, Kao JY, Lin H, Yang DY, Lai YY. 2011 Study of the anti-proliferative activity of 5-substituted 4,7-dimethoxy-1,3-benzodioxole derivitives of SY-1 from Antrodia camphorate on human COLO 205 colon cancer cells, ECAM, 2011: 450526 . no.1. (SCI)
Chen CH, Lin H, Chuang SM, Lin SY, Chen JJW 2010 Acidic stress facilitates tyrosine phosphorylation of HLJ1 to associate with actin cytoskeleton in lung cancer cells,Experimental Cell Research, 316:. pp.2910-2921 .
Lee YT, Lin H, Chen KY, Wu HS, Hwang MH, Yan SL 2010 Life-threatening hemobilia caused by hepatic pseudoaneurysm after T-tube choledochostomy: report of a case,BMC Gastroenterology, 10: 81.
Chen MC, Lin H, Hsu FN, Huang PH, Lee GS, Wang PS 2010 The involvement of cAMP in nerve growth factor-triggered p35/Cdk5 activation and differentiation in PC12 cells,American Journal of Physiology-Cell Physiology. pp.C516-C527. (SCI)
Kuo HS, Hsu, FN, Chiang MC, You SC, Chen MC, Lo MJ, and Lin H* 2009 Retinoic acid causes Cdk5-dependent apoptosis of cervical cancer cell line,Chinese Journal of Physiology, 52. pp.23-30. (SCI)
Lin H*, Chen MC, and Ku CT 2009 Cdk5 regulates steroidogenic acute regulatory protein (StAR) and androgen production in mouse Leydig cells Endocrinology, 150,pp.396-403 . (SCI)
Lin H 2009 The versatile roles of cyclin-dependent kinase 5 in human diseases,Adaptive Medicine, 1. pp.22-25.
Lee WJ, Wu CS, Lin H, Lee IT, Wu CM, Tseng JJ, Chou MM, and Sheu WHH 2009 Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-kB pathway Internatioanl Journal of Obesity 33,pp.465-472. (SCI)
Yan SL, Lin H, Kuo CL, Wu HS, Huang MH, and Lee YT 2008 Primary retroperitoneal mucinous cystadenoma,report of a case and review of the literature World Journal of Gastroenterology, 14. pp.5769-5772 .
Lee YT, Lin H, Wu HS, Kuo CL, Hwang MA, Tseng YC, and Hwang MH 2008 Large epidermoid cyst of the breast: report of a case Formosan Journal of Surgery 41,pp.221-225. (SCI)
Lin E, Lin H, Lin MS, Wu JCH, Chen WC, Chiu AW 2008 Laparoscopic excision of a paraganglioma located in the renal arteriovenous windows-a reasonable approach ,The Open Urology & Nephrology Journal, 1. pp.40-43.
Lin H*, Chen MC, Chiu CY, Song YM, and Lin SY 2007 Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells,Journal of Biological Chemistry 282. pp.2776-2784 . (SCI)
Lin H, Lin TY, and Juang JL*. 2007 Abl deregulates Cdk5 kinase activity and subcellular localization for amyloid-induced Drosophila neu Cell Death & Differentiation 14,pp.607-615 . (SCI)
Lin H, Juang JL*, and Wang PS* 2004 Involvement of Cdk5/p25 in digoxin-triggered prostate cancer cell apoptosis. Journal of Biological Chemistry 279,pp.29302-29307 . (SCI)
Lin H, Wang SW, Wang RY, and Wang PS*. 2001 Stimulatory effect of lactate on testosterone production by rat Leydig cells,Journal of Cellular Biochemistry 83. pp.147-154 . (SCI)
Lin H, Chien CH, Lin YL, Chen CF, and Wang PS*. 2000 Inhibition of testosterone secretion by S-petasin in rat testicular interstitial cells,Chinese Journal of Physiology 43. pp.99-103 . (SCI)
Chiao YC, Lin H, Wang SW, and Wang PS*. 2000 Direct effects of propylthiouracil on testosterone secretion in rat testicular interstitial cells,British Journal of Pharmacology 130. pp.1477-1482 . (SCI)
Chang LL, Lo MJ, Kan SF, Huang WJ, Chen JJ, Kau MM, Wang JL, Lin H, Tsai SC, Chiao YC, Yeh JY, Wun WS, and Wang PS* 1999 Direct effects of prolactin on corticosterone release by zona fasciculata-reticularis cells from mal Journal of Cellular Biochemistry 73,pp. 563-572 . (SCI)
Lin H, Tsai SC, Chen JJ, Chiao YC, Wang SW, Wang GJ, Chen CF, and Wang PS*. 1999 Effects of evodiamine on the secretion of testosterone in rat testicular interstitial cells,Metabolism 48. pp.1532-1535 . (SCI)
Huang WJ, Yeh JY, Tsai SC, Lin H, Chiao YC, Chen JJ, Lu CC, Hwang SW, Wang SW, Chang LS, and Wang PS*. 1999 Regulation of testosterone secretion by prolactin in male rats,Journal of Cellular Biochemistry 74. pp.111-118 . (SCI)
Kau MM, Lo MJ, Wang SW, Tsai SC, Chen JJ, Chiao YC, Yeh JY, Lin H, Shum AY, Fang VS, Ho LT, and Wang PS*. 1999 Inhibition of aldosterone production by testoterone in male rats.,Metabolism 48. pp.1108-1114 . (SCI)
Lo MJ, Kau MM, Chen JJ, Yeh JY, Lin H, Wang SW, and Wang PS 1999 Age-related differences in corticosterone secretion in female rats,Metabolism 48. pp.535-541 . (SCI)
Kau MM, Lo MJ, Tsai SC, Chen JJ, Lu CC, Lin H, Wang SW, and Wang PS*. 1999 Effects of estradiol on aldosterone secretion in ovariectomized rats,Journal of Cellular Biochemistry 73. pp.137-144 . (SCI)
Wang SW, Lin H, Hwang WJ, and Wang PS* 1999 Inhibition of testosterone secretion by digitoxin in rat testicular interstitial cell,Journal of Cellular Biochemistry 74. pp.74-80 . (SCI)
Lin H, Wang SW, Tsai SC, Chen JJ, Chiao YC, Lu CC, Huang WJ, Wang GJ, Chen CF and Wang PS* 1998 Inhibitory effect of digoxin on testosterone secretion through mechanisms involving decreases of cyc British Journal of Pharmacology 125,pp.1635-1640 . (SCI)
Wang SW, Lin H, Tsai SC, Hwu CM, Chiao YC, Lu CC, Chen JJ, Wang GJ, Chou CJ, Lin LC, and Wang PS*. 1998 Effects of methanol extract of Chansu on the hypothalamic-pituitary-testis function in rats,Metabolism 47. pp.1211-1216 . (SCI)
Doong ML, Lu CC, Kau MM, Tsai SC, Chiao YC, Chen JJ, Yeh JY, Lin H, Huang SW, Chen TS, Chang FY, and Wang PS* 1998 Inhibition of gastric emptying and intestinal transit by amphetamine through a mechanism involving a British Journal of Pharmacology 124,pp.1123-1130 . (SCI)
Tsai SC, Chen JJ, Chiao YC, Lu CC, Lin H, Yeh JY, Lo MJ, Kau MM, Wang SW, and Wang PS*. 1997 The role of cyclic AMP production,calcium channel activation and enzyme activities in the inhibitio British Journal of Pharmacology 122. pp.949-955 . (SCI)
Wang SW, Chiao YC, Tsai SC, Lu CC, Chen JJ, Shih HC, Chen YH, Lin H, Hwu CM, and Wang PS 1997 Inhibition of bufalin on pituitary and testicular function in rats,Journal of Pharmacology and Experimental Therapy 283. pp.528-532 . (SCI)

研討會論文

 
Yang MS, Hsu FN, and Lin H* 2008 2008 Changes of survival signalings between androgen-dependent and -independnet status in prostate cancer cells,The 23th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 29~30. (Oral Session #44) .
Lee, GS and Lin H*. 2008 2008 Roscovitine inhibits proliferation of prostate cancer cells possibly through Cdk5 inhibition,The 23th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 29~30. (Oral Session #8) .
Liu CY, Lin LL, Chiang MC, Lin H*. 2008 2008 The role of EGFR translocation in prostate cancer cells,The 23th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 29~30. (Oral Session #6) .
Lin LL, Hsu FN, and Lin H*. 2008 2008 Cdk5 interferes cyclin D1-dependent regulation of androgen receptor,The 23th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 29~30.
You SC, Kuo HS, Lin LL, and Lin H*. 2007 2007 All-trans-Retinoic Acid (RA)-induced protein interaction between Cdk5 and p21 CIP1 promote G1 arrest 15th Symposium on Recent Advances in Cellular and Molecular Biology,Kenting, Taiwan, 1-3, February, 2007. (Poster # 80) .
Lin H*, Chen MC, and Wang PS 2007 2007 Nicotine decreases testosterone production and Leydig cell viability through Cdk5 hyperactivation. Program and Abstract of the 40th Annual Meeting of the Society for the Study of Reproduction,San Antonio, USA 21-25, July, 2007. (poster # 414) .
Chiu CY, Peng HC, and Lin H*. 2007 2007 The role of cdk5 in GDNF-induced proliferation of human medullary thyroid carcinoma cells,The 22nd Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 17~18, 2007. (Oral Session #002) .
Hsu FN, Lin LL, Huang WH, and Lin H* 2007 2007 Cdk5 regulates proliferation of prostate cancer 5\r\ncells through androgen receptor phosphorylation 15th Symposium on Recent Advances in Cellular and Molecular Biology,Kenting, Taiwan, 1-3, February, 2007. (Poster # 74) .
Chen CC and Lin H 2006 2006 The role pf p35/Cdk5 in N-cadherin/beta-catenin-related adhesion in prostate cancer cells,The 21th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 18~19. (Poster Session #504) .
Ku CT, Chiu CY, You SC, and Lin H. 2006 2006 Retinoic acid-induced differentiation of prostate cancer cell line, DU145, is through upergulation o The 21th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 18~19.
Kuo HS, Chiang MC, Tseng SH, and Lin H. 2006 2006 Relationship between Cdk5/p35 and p53 proteins in retinoic acid-induced differentiation of HeLa cell The 21th Joint Annual Conference of Biochemical Science,Taipei, Taiwan, March 18~19. (Poster Session #294) .
Tseng CF, Hsu FN, and Lin H. 2006 2006 The involvement of Cdk5 and p35 in Her2/ErbB3-dependent androgen receptor signaling pathway,The 21th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 18~19. (Oral Session #028) .
Li GS, Tsai SY, and Lin H. 2006 2006 The role of Cdk5/p35 in NGF-induced differentiation of PC12, The 21th Joint Annual Conference of Biochemical Science. Taipei, Taiwan, March 18~19. (Poster Session #313) .
Lin H, Chen MC 2005 2005 The biological functions of cyclin-dependent kinase 5 and p35 protein in androgen production of mous Program and Abstract of the 38th Annual Meeting of the Society for the Study of Reproduction,Quebec, Cananda. 24-27, July, 2005 (Program # 751) .
Lin H. 2005 2005 The roles of cdk5 and p35 protein in androgen production of mouse leydig cells,The 20th Joint Annual Conference of Biochemical Science.
Lin H, Chen MC, Juang JL, and Wang PS 2004 2004 A possible curative effect of digoxin on prostate cancer,Twelfth International Congress of Endocrinology, Lisbon, Portugal. August 31~September 4 (Oral Session # 16) .

研究計劃

年度
補助機關
計畫名稱
計畫起迄日期
2022
國家科學及技術委員會
探討metformin對於CDK5相關之神經分化的影響與機制以及於妊娠型糖尿病的應用
2022/08/012023/07/31
2021
國家科學及技術委員會
探討metformin對於CDK5相關之神經分化的影響與機制以及於妊娠型糖尿病的應用
2021/08/012022/07/31
2020
科技部
探討metformin對於CDK5相關之神經分化的影響與機制以及於妊娠型糖尿病的應用
2020/08/012021/07/31
2019
科技部
探討CDK5蛋白於Aurora-A調控腫瘤細胞增生與轉移的重要性
2019/08/012020/10/23
2018
科技部
探討CDK5蛋白於Aurora-A調控腫瘤細胞增生與轉移的重要性
2018/08/012019/07/31
2017
科技部
探討CDK5蛋白於Aurora-A調控腫瘤細胞增生與轉移的重要性
2017/08/012018/07/31
2017
教育部
(研發處)厚植大學國際競爭力暨人才培育計畫
2017/11/162018/11/15
2016
行政院農業委員會種苗改良繁殖場
石斛預防與改善男性攝護腺肥大之效果及作用機轉
2016/02/202016/12/31
2015
科技部
探討Cdk5蛋白激酶經由調控細胞週期抑制蛋白p21表現而影響乳癌進展之生理機制
2015/08/012016/07/31
2014
科技部
探討Cdk5蛋白經由雌性激素受體相關途徑對於乳癌細胞生長的調控
2014/08/012015/10/31
2013
科技部
探討Cdk5蛋白經由雌性激素受體相關途徑對於乳癌細胞生長的調控
2013/08/012014/07/31
2012
其他-國科會
探討Cdk5蛋白經由雌性激素受體相關途徑對於乳癌細胞生長的調控
2012/08/012015/07/31
2012
科技部
探討Cdk5蛋白經由雌性激素受體相關途徑對於乳癌細胞生長的調控
2012/08/012013/07/31
2011
行政院國家科學委員會
探討Cdk5蛋白對於乳癌細胞生物功能的調控
2011/08/012012/07/31
2010
行政院國家科學委員會
Her2蛋白對於Cdk5相關之攝護腺癌細胞生長的調控
2010/08/012011/07/31
2009
行政院國家科學委員會
維生素甲酸對於Cdk5與p35蛋白相關之攝護腺癌細胞生長、分化與凋亡的影響
2009/08/012010/07/31
2009
行政院國家科學委員會
Her2蛋白對於Cdk5相關之攝護腺癌細胞生長的調控
2009/08/012010/07/31
2008
行政院國家科學委員會
維生素甲酸對於Cdk5與p35蛋白相關之攝護腺癌細胞生長、分化與凋亡的影響
2008/08/012009/07/31
2008
行政院國家科學委員會
Her2蛋白對於Cdk5相關之攝護腺癌細胞生長的調控
2008/08/012009/07/31
2007
行政院國家科學委員會
Cdk5蛋白對於多囊性卵巢疾病之扮演角色的探討 (WR2)
2007/11/012008/10/31
2007
行政院國家科學委員會
維生素甲酸對於Cdk5與p35蛋白相關之攝護腺癌細胞生長、分化與凋亡的影響
2007/08/012008/07/31
2006
行政院國家科學委員會
Cdk5/p35蛋白與活性對於攝護腺癌細胞之生長與演變的重要性(2/2)
2006/08/012007/07/31
2005
行政院國家科學委員會
Cdk5與p35蛋白對於萊氏細胞中雄性激素合成途徑的重要性
2005/01/012005/08/31
2005
行政院國家科學委員會
Cdk5/p35蛋白與活性對於攝護腺癌細胞之生長與演變的重要性(1/2)
2005/08/012006/07/31